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Dantrium
dantrolene (Dantrium): Muscle Relaxants & Antispasmodics
| Question | Answer |
|---|---|
| What is the prototype drug for muscle relaxants and antispasmodics? | dantrolene (Dantrium) |
| What is this drugs' purpose? | Acts directly on spastic muscles & inhibits muscle contraction by preventing release of calcium in skeletal muscles. |
| What conditions is this drug used to treat? (3) | 1.) Cerebral Palsy 2.) Spinal cord injury 3.) Multiple Sclerosis |
| What condition causes EXTREME muscle spasticity? | Malignant Hyperthermia |
| What is the primary adverse effect that this medication causes & how do we assess? | Muscle Weakness Assess by asking if they can pick up a pencil, exhibit difficulty tying shoes/brushing teeth, etc. |
| What labs should we obtain before & monitor throughout treatment? | Liver function studies |
| When beginning treatment, it is important to start with a __________ dose | Low |
| Do/do not stop taking this medication abruptly. | Do NOT |
| Malignant Hyperthermia: Indication | Rapid rise in body temperature! Sometimes as high as 106-107*F |
| Malignant Hyperthermia: Treatment (5) | 1.) Stop taking drug first! 2.) Establish airway (oxygen: regular or intubate) 3.) Give Dantrium 4.) cooling blanket 5.) Tylenol (oral=conscious, IV=unconscious) |
Created by:
amydawsonpool13
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