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Endocrine System
WVSOM: Endocrine System
Question | Answer |
---|---|
What are the three cell types found in the pars distalis | Acidophils, basophils and chromophobes |
What do somatotrophs secrete | Growth Hormone (GH) |
What do mammotrophs secrete | Prolactin |
What are the acidophils | Somatotrophs and mammotrophs |
What are the basophils | Thryotrophs, Gonadotrophs, and corticotrophs |
What do the thryotrophs secrete | TSH |
TSH causes the release of what | thyroxine and triiodothryonine |
Gonadotrophs release what | FSH |
What do Corticotrophs release | ACTH |
What does the release of ACTH trigger | The release of glucocorticoids |
What is another name for the posterior portion of the pituitary | pars nervosa (neurohypophysis) |
What are Herring bodies | Stores of oxytocin and ADH in the axon terminals |
What are pituicytes | support cells found in the pars nervosa |
What does the release of oxytocin cause | smooth muscle contraction, milk release, and uterine contractions |
What organ/gland appears to look like bubble gum | thyroid |
Another name for parafollicular cells | C-cells |
What do C-cells secrete | calcitonin |
Are C-cells part of the epithelium in the thyroid | NO! |
Calcitonin limits the activity of what | osteoclast |
Would high or low levels of blood calcium stimulate calcitonin | high |
Principal cells are another name for what | Follicular cells |
What do principle/follicular cells release | T3 and T4 hormones |
What do T3 and T4 hormones cuases | increase in basal metabolic rate, increase in CO, increase food consumption, cartilage growth, and other energy requring cell functions |
What mainly makes up the colloid in the thyroid gland | inactive thyroid hormone (thryoglobulin) |
What is hashimoto's disease | An autoimmune disease that causes destruction of the thyroid resulting in hypothyroidism |
What is another name for hyperthyroidism | thryotoxicosis |
Symptoms of hyperthyroidism | fatigue, weight loss, rapid pulse, red eyes, nervousness, sweating, heat intolerance, etc... |
How many parathyroid glands usually exist | 4 |
Where are they located (general) | posterior of thyroid |
PTH is released by what gland | parathyroid glands |
What action does PTH have on osteoclast | increases their activity |
What else does PTH regulate | phosphate levels |
What function does the pineal gland serve | 24 hour cyclic release of hormones |
What are three symptoms releated to hyperparathyroidism | kidney stones, bone loss, and muscular weakness |
Surgical removal of the thyroid could result in what disorder | hypothyroidism |
Low blood calcium levels could maifest as what | muscle cramps and tingling in fingers and toes |
The pineal gland works in harmony with what other gland | hypothalamus |
From superficial to deep, name the zones adrenal cortex | zona Glomerulosa, zona fasciculata and zona reticulais |
What does the zona glomerulosa secrete/control | mineralcorticoids (mainly aldosterone) in response to angiotensin II |
What does the cytoplasm of the zona glomerulosa stain | acidophilic |
What is the thickest layer of the cortex | zona fasciulata |
What does the zona fasiculata secrete | glucocorticoids (cortisol and corticosterone) in response to ACTH |
What does the zona reicularis secrete | small amounts of glucocorticoids, and DHEA and androstenedione |
What is Cushings syndrome | hypersecretion of cortisol and androgens |
What is addisons disease | hyposecretion of adrenal cortex |
Name the three cell types in the islets of langerhans | Alpha cells, beta cells, and delta cells |
Describe Alpha cells | make up 20% of cells and secrete glucagon |
Describe Beta cells | make up 70% of cells and secrete insulin |
Describe Delta cells | make up 5-10% and secrete somatostatin |
Where do centerendocrine cells hang out in the GI | crypts of lieberkuhn |