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Antiarrhytmic Agents
Quiz 6
Question | Answer |
---|---|
Group of drugs used to treat abnormal electrical activity of the heart. Limit electrical activity to normal conduction pathways and decrease abnormally fast heart rates. | Antiarrhythmic Agents |
Group of drugs that blocks the movement of Na into cells of the cardiac conduction system. This group is declining in clinical use. | Class I Sodium Channel Blockers |
Subgroup used to prevent recurrence of A-fib and other atrial arrhythmias. Also suppresses ventricular ectopic beats and can be used to treat persistent ventricular tachycardia. | Class IA |
Procainamide Hcl is what type of drug? | Class IA |
Subgroup and drug? Helps prevent recurrence of A-fib. Also suppresses atrial and ventricular ectopic beats and self-limiting bursts of arterial or ventricular tachycardia. | Quinidine Sulfate (Class IA) |
Subgroup and drug? Used to treat ventricular ectopic beats in myocardial ischemia, convert ventricular tachycardia, reduce self-limiting bursts of ventricular tachycardia. | Lidocaine Hcl (Class IB) |
Subgroup and drug? Maintain sinus rhythm after ventricular fibrillation has been converted. Considered DOC for treating serious ventricular arrhythmias associated with acute MI, cardiac surgery, etc. | Lidocaine Hcl (Class IB) |
Subgroup and drug? Decreases automatically in the ventricles, but has little effect on arterial tissue. Not used for atrial arrhythmias. Controversial. Short 1/2 life. Given with IV bolus, then continuous IV infusion. | Lidocaine Hcl (Class IB) |
Subgroup and drug? Reduces ventricular ectopy. Given PO. May require a loading dose. | Mexiletine Hcl (Class IB) |
Subgroup and drug? Oral equivalent of Lidocaine. Used to suppress ventricular ectopy and reduce frequency and duration of self-limiting bursts of ventricular tachycardia. | Tocainide Hcl (Class IB) |
Subgroup and drug? Indicated only for the use of life-threatening ventricular arrhythmias. May aggravate or initiate new arrhythmias. | Flecainide (Class IC) |
Group of drugs that block sympathetic nervous stimulation of beta receptors in the heart and decrease risk of V-fib. | Class II Beta Adrenergic Blocker |
Group of drugs most often used to slow ventricular rate of contraction of SVT. Used extensively because of their effectiveness and ability to reduce mortality, including post MI and HF. | Class II Beta Adrenergic Blocker |
Specific drug given PO for chronic therapy to preveny ventricular arrhytmias precipitated by exercise. | Acebutolol |
What type of drug is Acebutolol? | Class II Beta Adrenergic Blocker |
Specific drug used to treat sudden onset of self-limiting atrial or ventricular tachycardia. Not used to terminate acute ventricular tachycardia. Best used in patients with arrhythmias associated with excess catacholamines. | Propranolol Hcl |
What type of drug is Propranolol Hcl? | Class II Beta Adrenergic Blocker |
Group of drugs in which clinical use continues to increase. Prolong action potential, slow repolarization, and prolong refractory period in atria and ventricles. Can be used for ventricular arrhythmias are ineffective. | Class III Drugs that Prolong Repolarization |
Specific drug used for treatment of paroxysmal SVT. Ineffective in treatment of other arrhythmias. Has serum half-life of 10 seconds, and high degree of effectiveness. | Adenosine |
Adenosine is what type of drug? | Class III Drugs that Prolong Repolarization |
Specific drug indicated for life-threatening ventricular ectopy. Used to reduce frequency and duration of persistent ventricular tachycardia unresponsiveness to other antiarrhythics. Requires loading doses. | Amiodarone HCL |
What type of drug is Amiodarone HCL? | Class III Drugs that Prolong Repolarization |
Specific drug used only for short-term therapy in life-threatening conditions. Prevention and treatment of V-fib and ventricular tachycardia unresponsiveness to other treatments. Used when lidocaine and procainamide are ineffective. | Bretylium tosylate |
What type of drug is Bretylium tosylate? | Class III Drugs that Prolong Repolarization |
Group of drugs that block movement of Ca into contractile myocardial cells. Act primarily against tachycardias at the SA and AV node. Effective only in SVT. | Class IV Calcium Channel Blockers |
Specific drug blocks influx of Ca across the channels of the myocardial electrical cells. Slows conduction rate between the atria and ventricles. | Verapamil Hcl |
Specific drug given IV to convert rapid heart rate of SVT. Reduces rate of ventricular response in patients with A-fib or atrial flutter by blocking conduction through the AV node. May be given PO to prevent recurrent SVT in adults. | Verapamil Hcl |
What type of drug is Verapamil Hcl? | Class IV Calcium Channel Blockers |
Specific drug given PO to prevent recurrent SVT and to decrease ventricular response in patients with chronic A-fib or flutter. Slows ventricular response in atrial and supraventricular tachycardias. | Diltiazem Hcl |
What type of drug is Diltazem Hcl? | Class IV Calcium Channel Blockers |
Specific drug given IV in the prevention of torsades de pointes and treatment of digitalis-induced arrhythmias. | Magnesium Sulfate |
Specific drug given IV to treat the arrhythmias associated with dig toxicity. Shortens prolonged conduction through the AV node. Onset of IV action is 5 minutes. | Phenytoin |