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Sarah's Patho Group

Test One

QuestionAnswer
What is the control center of the cell? Nucleus
Tay-Sach's disease results from a dysfunction of which cellular component? Lysosomes
What cellular component is similar to lysosomes by contains special enzymes that help control free radicals? peroxisomes
What part of the cell holds the cell together, provides a protective barrier, and contains antigens that label the cell as self or non-self? Cell membrane
This pathway for energy production requires oxygen. Aerobic
This pathway for energy production occurs in the cytoplasm. anaerobic
The byproduct of the anaerobic pathway that can cause acidosis should too much accumulate. lactic acid
The process by which substances move from areas of greater to lesser concentration in an attempt to reach uniform distribution. diffusion
Diffusion of water through a semipermeable membrane along a concentration gradient. osmosis
The cellular eating of microorganisms or damaged cells. phagocytosis
Parkinson's disease is a problem of which type of messenger? chemical
When the body cells are electrically polarized at rest and the inside of the cell is more negatively charged than outside. resting membrane potential
This is responsible for sodium ions being more concentrated outside the cell and potassium ions being more concentrated inside the cell. Sodium-Potassium pump
An electrical signal that moves very quickly from cell to cell. Action potential
The initial stimulus that causes the cell membrane to become more permeable to sodium. Depolarization
After depolarization, the cell becomes negatively charged again. Repolarization
An increase in cell size so that it can meet the increased work demands. Hypertrophy
When the cell becomes smaller in an attempt to decrease it's oxygen and energy needs. atrophy
An increase in the number of cells. hyperplasia
When a cell changes from one type to another that is better able to survive in adverse circumstances. metaplasia
Deranged cell growth. dysplasia
Atoms that are highly unstable and can damage parts of the cell. free radicals
A disease process that is associated with uncontrollable cell growth, infiltration into surrounding tissues causing tissue/organ dysfunction and changes the characteristics of normal cells. Cancer
The phase of the cell cycle that prepares to divide. G1
The phase of the cell cycle where DNA synthesis occurs. S
The number of chromosomes made in mitosis. 46
The number of chromosomes made in meiosis. 23
The phase of cell cycle that continues protein and RNA synthesis. G2
The phase of the cell cycle where cell division/mitosis occurs. M
The resting phase of the cell cycle. G0
The reproduction or division of somatic cells capable of reproducing. Mitosis
The reproduction of germ cells. Meiosis
The process by which cells develop specialized structures and functions as regulated by genetic programming. Differentiation
A sex-linked genetic disorder defined by deficiency or nonfunction of factor VIII (clotting factor). Hemophilia A
An autosomal dominant disorder that affects the connective tissues. Marfan's Syndrome
An autosomal recessive disorder that causes defective hemoglobin molecules. Sickle Cell Anemia
A chromosomal disorder that occurs when chromosome 21 has three copies instead of two. Down syndrome
When alleles are the same. homozygous
When alleles are different. heterozygous
A trait that is only expressed on the homozygous pairing. recessive
A trait that is expressed on either a homozygous or heterozygous pairing. dominant
An error in DNA replication that changes the genetic code. gene mutation
The production and development of blood cells. Hematopoiesis
When there are too many red blood cells making the blood more viscous and ready to form clots. polycythemia
Where are red blood cells made? Bone Marrow
What is released by the kidneys that signals to the bone marrow that more red blood cells need to be made in response to hypoxia? Erythropoietin
This blood group has A antigens and B antibodies. Type A
This blood group has B antigens and A antibodies. Type B
This blood group has both A and B antigens and neither antibodies. Type AB
This blood group has neither A or B antigens but has both A and B antibodies. Type O
This blood group can be donated to any ABO blood type. Type O
This blood group can receive blood from either A or B blood type. Type AB
This Rh group only develop antibodies if exposed to Rh-positive blood. Rh-negative
A nutritional deficiency in this mineral can lead to microcytic and hypochromic cells. Iron
This type of anemia is a result of bone marrow failure. aplastic anemia
B12 and folic acid are needed for: DNA synthesis
Platelets are produced in the bone marrow and stored in the: Spleen
A patient that bruises easily, has petchiae, and suffers from epistaxis may suffer from which blood disorder? thrombocytopenia
The first stage of hemostasis that lessens the blood loss. Vasoconstriction
The second stage of hemostasis that is involved in platelet aggregation. Formation of the platelet plug.
The third stage of hemostasis that develops the fibrin clot to stabilize the platelet plug. Blood coagulation
The fourth stage of hemostasis that brings the edges of the broken vessel back together. Clot Retraction
The final stage of hemostasis that allows blood flow to be reestablished. Clot dissolution
This fat soluble vitamin is needed for coagulation. Vitamin K
A disease process characterized by blood coagulation and bleeding occurring at the same time. Disseminated Intravascular Coagulation
This disease process of the white blood cells is characterized by an increased number of abnormal white blood cells. leukemia
A function of the immune system is to detect and respond to abnormal cells that develop in the body. Cancer Surveillance
What are the two primary lymphoid organs? bone marrow and thymus
Response is the same regardless of the antigen. Innate resistance
The first line of defense. Skin and mucous membranes
Type of WBCs that consist of neutrophils and monocytes/macrophages. phagocytic
Cells that are programmed to automatically kill tumor cells and virus-infected cells by releasing toxic substances. natural killer cells
Small hormone-like proteins the help regulate immune response. cytokines
A cascade of plasma proteins that, when activated, enhances inflammation and WBC efficiency. complement system
Also known as CD4 cells. Helper T cells
Also known as CD8 cells. Cytotoxic T cells
These cells remain in the body for a long time and enables a more rapid response on repeat exposure to an antigen. Memory cells
These cells stop the immune response once the foreign agent is destroyed. Suppressor T cells
These cells secrete antibodies/immunoglobins which bind to and aggregate antigens to aid in their removal by phagocytes. plasma cells
This class of immunoglobins (Ig) crosses the placenta and provides protection for newborns for the first few months. IgG
This is the main Ig in the body secretions and protects mucous membranes. IgA
This Ig is the first to appear in response to an antigen, it's presence usually suggests a current infection by the pathogen. IgM
This Ig is found on the cell membrane of B lymphocytes and binds with an antigen to stimulate B cells to produce other specific immunoglobins. IgD
This Ig is involved in allergic reactions and parasitic infections. IgE
This type of immunity is acquired through vaccination or by having the disease Active immunity
This type of immunity is acquired by receiving antibodies or immune cells from another source (is short-term protection). Passive immunity
The absence of an immune repsonse directed against a person's own antigens. self-tolerance
Created by: lysistrata117
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