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Nina's questions
Pharm (Test 3)
Question | Answer |
---|---|
Propofol induces a state of general anesthesia by what action? | activation of GABA to induce the opening of Cl- channels |
What makes propofol an ideal drug for the outpatient setting? | rapid metabolic clearance, short 1/2 life, antiemetic effects |
Which of the following is a factor that exacerbates Propofol induced hypotension? | speed of injection |
Which of these patient types is more prone to have a significant drop in CO w/ propofol? | 60 y/o w/ a history of impaired ventricular function |
What makes propofol a great choice for use w/ LMA? | upper airway reflexes are depressed better than barbiturates |
What of the following is not a contraindication for propofol administration? | chronic history of asthma |
Clonus, spontaneous movement, and twitching after receiving propofol indicates? | excitatory phenomenon |
Which of the following is true regarding propofol administration? | admin. should be complete w/in 6hrs, composition supports bacterial growth, should be used w/in 6hrs even if containing preservatives |
What is the appropriate dose of propofol for induction of a healthy adult? | 2-2.5mg/kg |
What's the propofol infusion dose for moderate sedation for a healthy pt? | 50mcg/kg/min |
Ketamine is classified as... | dissociative IV anesthetic |
Which is true of ketamine's binding action? | binds non-competitively to NMBA receptors |
Should be administered prior to ketamine to avoid negative hallucinogenic effects? | benzos |
Why would a prudent CRNA administer glycopyrrolate prior to giving a pt ketamine? | antisialogogue effect |
Selection of ketamine for induction for an "acute abdomen" would be appropriate d/t? | it would maintain CO and BP |
NSAIDS are contraindicated in which pt? | aspirin allergy, nasal polyps, asthma, and renal failure |
What is the MOA for NSAIDS? | inhibits cyclooxygenase and prostaglandinsynthesis pathways |
Slight BP elevation may be seen w/ NSAID administration d/t? | inhibition of prostaglandins |