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Pharm 8 Thyroid
Question | Answer |
---|---|
What is secreted when there is a decrease in T3, T4, or both? | TSH |
Where is TSH secreted from? | Anterior Pituitary Gland |
A decrease in T4 and an increase in TSH indicates what? | Primary Hypothyroidism |
Normal TSH value is? | 0.5-4.0 |
A lack of TSH and decrease in T3 and T4 indicates what? | Secondary Hypothyroidism |
Apathy, cold intolerance, Memory impairment, slow speech, edema, constipation, weight gain, and abnormal menses are s/s of? | Hypothyroidism |
Who is at risk for hypothyroidism? | Risk increased in women >60 yo |
What happens with Hasimoto Thyroiditis? | Immune system attack on thyroid gland |
TSH secretion from the gland is a ________ feedback mechanism | Negative |
CNS Stimulation. S/S include nervousness, irritability, heat intolerance, perspiration, hand tremors, palpitations, difficulty sleeping, weight loss, and thinning skin. | Hyperthyroidism |
Enlargement of the thyroid gland. May develop when too much or too little thyroid hormone. Most common cause is lack of iodine in diet. | Goiter |
Thyroid gland not working or removed. | Synthroid |
Natural or synthetic. Contain T3, T4 or both. Act as replacement or substitute when body's hormone levels can't meet its needs. | Hypothyroid Agents |
Levothyroxide sodium, Liothyronine sodium (T3) and Liotrix (synthetic T3 and T4) are what types of agents? | Hypothyroid Agents |
Agents that interfere with hormone synthesis. Modify tissue response to hormones. Destroy the thyroid gland. | Hyperthyroid Agents |
Inhibits synthesis of hormones. Can be used for thyroid Sx and with radioactive iodine therapy. | Methimazole (Hyperthyroid Agent) |
Treats thyroid crisis (thyroid storm). Inhibits conversion of T4 to T3. DOC in pregnancy (safer for fetus). Can be used to prepare thyroid gland before Sx or radioactive iodine therapy. | Propylthiouracil (PTU) (Hyperthyroid Agent) |
Used to prepare thyroid gland prior to surgery. Firms gland and decreases its vascularity. | Iodine |
Preferred treatment for hyperthyroidism. Exposes thyroid to altering radiation, thus destroying the gland. | Radioactive Iodine 131 |
Beta adrenergic blocker used to treat cardiovascular symptoms of hyperthyroidism. Used prior to thyroidectomy to treat s/s before other agents become effective, and for thyrotoxic crisis. | Propranolol |
Thyroid agents may precipitate _________. Obtain order for EKG and nitroglycerin if develops. | Chest Pain/Angina |
Diarrhea, abdominal cramps, weight loss, tachycardia, angina, nervousness, and fever are s/s of what? | Thyrotoxicity |