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intro to Pharm
Question | Answer |
---|---|
3 most important characteristics of any drug | effectiveness safety selectivity |
is it possible to have a selective drug? | no. because all drugs have side effects |
four phases of pharmacokenetics | absorption, distribution, metabolism, excretion |
define pharmacodynamics | nature and intensity of the response that the drug has on the body |
which member of the health care team is most likely to observe and evaluate and intervene if required | the nurse |
3 most importnat goals of pre-admnistration assessment | evaluate effects, identify high risk patients, assess for self care |
what factors can predispose an indvicual to adverse reactions from drugs? | allergies, pregnancy, age, genetics, pathological disease (kidney and liver) |
what measures help reduce adverse reactions of medication administration | a through patient history to identify those at high-risk and patient education |
what is a blinded study | participants do not know if they belong to control or test group |
what type of research is required to assess drug therapies? | the randomized controlled trial is required for all new medications |
which ammendment strengthened drug regulation after the Thalidomide tragedy in Europe? | The harris-Kefauver Ammendment to the FDA and the Cosmetic Act of 1962 |
what is the purpose of having a trade name? | trade names are easy to recall and pronounce; good for marketing |
what is one of the problems wiht trade names | using 2 brand named drugs with the same ingredient may lead to overdosing |
what are some limitations in the testing process used to bring drugs to market? | information on women and children are limited new drugs likely to have adverse effects not detected in clinical trials |
cost to develop a new drug in the US | can exceed 800 million dollars |
four drugs that cuase the most adverse reactions | blood thinners, insulin, digoxin, sulfonureas |
what setting do most drug errors occur? | outpatient, ambulatory |
which is correct? a. 2.0 mg b. 0.2mg c. .2 mg d. 2mg | b and d |
MS (morphine sulfate), MSO4 and MSGO4, > (greater than), < (less than), abbreviations for drug names, apothecary units, @, Cc, ug....all have one thing in common. What is it? | abbreviations on the "Do Not Use List" |
which scheduled drugs can NP's prescribe in the state of Florida? | none |
schedule II drugs | codeine, fentanyl, hydromorphone, morphine, dextroamphetamine |
schedule III drugs | buprenoprhine, anabolic steroids |
schedule IV drugs | benzodiazepines |
what schedule drugs require a hard copy of Rx? (cannot be called in) | schedule II |
equal active ingredients, dosage form, identical disintegration, rate of absorption, efficacy, and safety are features of what type of drugs | generic bioequivalent drugs |
a warning that medical sutudies indicate that the drug carries a significant risk of serious or life-threatening adverse effects is known as _______ | black box warning |
examples of drugs with black box warning | SSRI's, antipsychotics, metformin, salmeterol |
which class of antihypertensives are recommended for African Americans? | diuretics, then CCB's |
activity of CYP 2D6 is (higher/ lower) in Asians and may require (higher/ lower) doses of drugs utilizing this metabolizing enzyme? | lower, lower |