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Substance abuse
Stack #210793
Question | Answer |
---|---|
CNS depressants- benzodiazepines... action | potentiate GABA inhibitor for sleep and anxiety= slower pulse, breathing, feeling of wellbeing |
Benzodiapenes overdose effects on body | nystagmus, hallucinations, slurred speech, ataxia, coma, weakness, hypotension, respritory depression |
Treatment of benzodiazepines overdose | Narcan and Flumazenil (benzodiazepine antagonist) |
withdrawal symptoms of benzodiazepenes | convulsions, confusion, delusions, tachycardia, depression, paranoia, muscle cramps, pain, insomnia, |
Reason for Benzodiazepine withdrawal symptoms | cuz GABA is taken away so the body is in the excitatory state |
Tx of withdrawal Benzodiazepines... | take off drug, switch to quidose of diazepam and chlordiazepoxide (librium) |
Heroin is a category of | Opioids |
Heroin desired effects | sedation, euphoria, anxity reduction, pain relief |
Heroin adverse effects | respritory depression, constipation, hypotension, urinary retention, COX depression, spasms, vomiting, miosis |
Overdose of heroin | shallow breathing, pulmonary edema, coma, death, convulsions |
Tx of heroin overdose | methidone, buprenorphine (cant overdose as easily), Naltrexate (short-acting used in overdose) |
withdrawal of heroin | sweaty, malaisse, enxiety, depression, extra sensation of genitals, erection, yawn, sneezing, tears, cold serats, fever, N/V/D, itchy blood, restless syndrome (over 6-24 hrs after stop) |
Tx of heroin withdrawal | Methidone, Buprenorphine, Valium, Naloxone |
Meth desired effects | euphoria, intense physical activity, |
meth adverse effects | anxiety, confusion, paranoia, hallucinations, violance, decreased appetite, dental deterioration, HR and RR spike, stoke and hyperthermia |
Overdose adverse effects | hyperthermia, convulsions |
Tx of meth | deal with hyperthermia (cool bath), anticonvulsive drugs, no pharmaceudical tx, followed by depression= antidepressants |
withdrawal sx of meth | irritable, restless, depression, anxiety, angry, confusion, not motivated |
Tx of meth withdrawal | No drug for tx. supportive care, teach, sleep, nutrition, acknowledge depression |
PCP is a | Hallucinogen |
PCP effects | numbness, slurred speeach, moderate analgesic, |
PCP overdose effects- RED DANE | RageErrythmaDilated pupilsDilusionsAmnesiaNisthegmaExcitationAlso- hallunication, long term schetzophrenia |
PCP tx of overdose | no drug= keep in calm environment |
withdrawal PCP | memory loss, difficult with speech, wt. loss, mood disorders (violent, suisidal) |
Tx of withdrawal | Halodal or Lorazepam |
Inhalants desired effects | similiar to alcohol |
inhalants tx of overdose and withdrawal | supportive care |
Inhalants withdrawal sx | restlessness, nausea, sweating, anxiety, |
marijuana desired effects | euphoric high |
marijuana adverse effects | memory and learning perception decreased, decreased ability to solve problems and react |
overdose marijuana effects | psychosis, severe paranoia, fatigue, pass out from fatigue(sometimes before reach overdose) |
Tx of marijuana overdose | supportive care |
withdrawal sx of marijuana overdose | restlessness, irritability, insomnia, craving, strange dreams, decreased appetite |
Tx of withdrawal | counseling, group meetings |
Nicotine desired effects | release of dopamine- pleasure |
adverse effects of nicotine | if maternal smoking=decreased birth wt. cancer, lung disease, heart disease, stroke |
Nicotine causes... | adrenal gland to release epinephrine which stimulated sumpathetic NS to increase BP, RR, HR. Glucose released into blood and insulin is inhibited |
Tx of nicotine overdose | monitor VS, meds to tx symptoms, charcoal if chewable form |
Withdrawal sx of nicotine | intense craving, irritable, H/A, hard to concentrate, drowsiness, trouble sleeping, increased appetite and wt. gain |
tx of withdrawal for nicotine | Gum and patch to decrease symptoms of withdrawal. Chantix to reduce symptoms (scary dreams as side effect) |
Anabolic adrenergic steroids desired effects | enhances performance and appearance |
adverse effects of steroids | facial hair, deep voice, menstrual changes, growth halted (teens), severe acne, jaundice, tumors, cancer, |
Overdose of steroids | cant overdose on |
Tx of steroids | education, hormonal meds for hormonal balance |
withdrawal sx of steroids | weakness, fatigue, nausea, diarrhea, abdominal pain, acute psychosis |
tx of withdrawal sx of steroids | no meds, supportive therapy, efucation, meds to restore hypothalamic release of hormones |
Med to block intended effect of substanse (loose benefit), makes it less appealing | Naltrexone similiar to Narcan |
Med that causes adverse effect with use of substance | Antabuse |
Drug that reduces withdrawal symptoms | Campral restoring neurotransmitter balance |
Med that provides tapering with safer drug | Methidone (opioid that is safer, long acting, keeps person out of withdrawal) |
The most abused substance in the US is... | alcohol |
Alcohol is ________-soluble | water: causing rapid absorption into the bloodstream |
Alcohol crosses the ______ acts on CNS | Blood Brain Barrier |
Gaba is enhanced with alcohol causing | slowed down brain function (cuz GABA is an inhibitory neurotransmitter) |
Alcohol inhibits this neurotransmitter | glutamate |
poor judgement, relaxation and ease of speaking are effects of alcohol of what part of the brain? | Cerebral Cortex |
Exagerated emotions, memory loss are effects of alcohol on this part of brain... | Limbic system |
Inability to write and walk is due to alcohol on this part of brain... | Cerebellum |
Inhalants adverse effects | dizziness, slurred speech, lethargy, depressed reflexes, decreased muscle strength |
Nitrates (inhalant) causes | increased sexual pleasure and performance |
Overdose of inhalants | convulsions/seizures, choking, coma, asphyxiation, suffocation, death |
meds to tx of alcohol withdrawal | Ativan (lorazepam), Valium (diazepam), Librium and Serax |
Most serious withdrawal period is | 24-48 hrs because of seizures, which puts at risk for aspiration, O2 deprivation and injury from thrashing |
Hallucinations, disorientation, tachycardia, HTN, Diaphoresis occur ____ after last drink | 2-3 days |
insomnia, milk anxiety, headache, tremors, HTN are what stage of alcohol withdrawal | 4-12 hours after last drink |
At what time after last drink of alcohol would you experience hallucinations? | 12-24 hours |
withdrawal sx of alcohol can last up to.... | 5-6 days |
inhibition of ADH, with decreased sexual performance and erectile dysfunction is due to effect of alcohol on this part of brain... | hypothalamus |
decreased level of consiusness, decreased respiratory rate is due to effect of alcohol on this part of brain... | brain stem |
This is the cause of thiamine deficiency causing confusion, confabulation, and amnesia... | Wenicke-Korsakoff syndrome |
long term effects of alcohol on body... | cardiomyopathy, pancreatitis, hepatitis, cirrhosis of liver, sexual dysfunction, myopathy (vitamin B defieciency), peripheral neuropathy, malnutrition |
Short term effects of alcohol on body... | Irritated GI lining, vasodilation, muscle weakness and swelling, increased urination (cuz ADH inhibited), hypoglycemia(liver is busy with detox of alcohol and cant from glucose) |
Becoming more self-confident and daring with a poor judgement, and difficulty with fine motor movement is ________ stage of intoxication of alcohol. | Euphoria |
sleepy, trouble comprehending, slow reactions, loss of balance, blurry vision, decreased sensory reception is _____ stage of alcohol intoxication | Lethargy |
Confusion, dizziness, sleepy, highly emotional, slurred speech, and does not percieve pain as normal individual is _______ stage of intoxication of alcohol | Confusion |
Cant respond to stimuli, cant walk, may vomit, lapse in and out of consiousness is ___________ stage of ETOH intoxication | Stupor |
Unconcious, decreased reflexes, decreased body temperature, slow, shallow breathing, death may occur is ___________ stage of ETOH intoxication | Coma |
CNS fails, breathing stops is ________ stage of ETOH intoxication | Death |
LISt the most common abused perscription drugs in order.... | Opiods, CNS depressants (benzodiazepenes), and Stimulants (tx of ADD and narcolepsy) |