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Mood disorders
Stack #210861
Question | Answer |
---|---|
Define dysthymic disorder | Long-term depression with less severe symptoms that may not disable a person but prevents one from functioning normally |
Post-partum depression occurs | after delivery |
Seasonal affective disorders | occurs during the winter months |
Transient stage of depression is marked with... | normal every day responses to dissapoitments and stress |
Mild stage of depression is marked with... | A grief response |
Moderate stage of depression is marked with | long term symptoms but not disabling |
Severe stage of depression | this is the actual major depressive disorder |
Biological theory of explanation: Biochemical | Imbalance of 3 neurotransmitters serotonin, norepinephrine and dopamine |
Biological theories of explanation: Neuroendocrine | imbalance of normal hormonal system |
Psychosocial theories of depression: Psychoanalytical | Freud's theory: depression is anger turned inward |
Psychosocial theories of depression: Learning | Learned helplessness, repeated failure leads to giving giving up |
Psychosocial theories of depression: Object loss theory | Depression is due to the abandonment or loss in the first months of life |
Psychosocial theories of depression: Cognitive theory | Pessimistic, negative thinking, high expectation of self leads to depression |
Transactional model for depression | No single explanation but a combination of all theories; multiple causation |
This type of antidepressant is rarely used... | Monoamine oxidase inhibitors |
Phenelzine (Nardil) and Parnate are examples of... | MAOI's |
Prozak is used | is safe to use under 18 years of age |
MAOI's work by | inhibiting MAO enzyme system that breakdown 3 neurotransmitters |
Hypertensive crisis can occur when taking MAOI's and ingestion of _______ | Tyramine (in cheese, chocolate, wine) |
Tricyclics (TCA's) act by ... | inhibiting reuptake of serotonin and norepinephrine |
amytriptyline (Elavil), and doxepin (Sinequan) are examples of.... | TCA's |
Which category of antidepressants has an anticholinergic side effect (dry mouth, constipation, urinary retention, blurred vision), and overdose can be lethal? | TCA's |
Which category of antidepressants block reuptake of serotonin and leave more on the synapse? | SSRI's (selective serotonin reuptake inhibitors) |
agitation, insomnia, tremor, sexual dysfunction, anxiety, drowsiness, wt. gain are side effects of... | SSRI's |
Which class of antidepressants is the safest with less side effects? | SSRI's |
citalopram (Celexa), paroxetine (Paxil), Fuoxetine (prozak), escitalopram (Lexapro) and sertraline (Zoloft) are examples of.... | SSRI's |
SSNRI's act by | inhibiting serotonin and norepinephrine reuptake in the CNS |
ibupropion (Wellbutrin) and trazadone (Desyrel) are examples of | Atypical antidepressants |
SSNRI's side effects include... | urinary retention, abnormal dreams, sexual dysfunction |
Atypical antidepressants work by... | Decreasing dopamine uptake- their action is unclear |
venlafaxine (Effector) and dulozetine (Cymbalta) are examples of... | |
Benefits of atypical antidepressants | no weight gain, and increase sexual activity.But increase risk for seizures |
Central Serotonin Syndrome is... | too much available serotonin (caused by taking 2+ meds that increase level) |
Taking St. John's Wart can increase risk of... | central serotonin syndrome |
S/Sx of Central Serotonin Syndrome includes | confusionm twitching, muscle spasms, uncoordinated ataxia, fever, delirium, HTN, and cardiovascular collapse. |
When meds and therapy is ineffective of treatment of depression... | Electroconvulsive Therapy |
Cyclothymia is | a milder form of bipolar disorder with less severe manic episodes (hypomania) and less severe depressive episodes |
Litium is a | mood stabilizer |
Lithium acts by | effecting Na transport in the nerve cells, help stabilize |
dizziness, drowsiness, wt. gain, bloating, fatigue, increased thirst, polyuria, hyponatremia (predisposes toxicity of) are side/effects of _______ | Lithium |
What medications need to have their therapeutic blood levels monitored? | Lithium and anticonvulsants (Depakote, Tegretol, Lamictal) |
Anticonvulsants are meds used for bipolar disorders that act by | increasing levels of GABA n the CNS |
valpriate (Depakote), carbamazepine (Tegretol), and lamotrigine (Lamictal) | anticonvulsant drugs used to tx mood disorders |
When unresponsive to lithium or anticonvulsants use.... | antipsychotics |
Antipsychotics work by | blocking dopamine receptors in the brain |
examples of antipsychotics include | Olanzapine (zyprexa), quetiapine (Seroquel), risperidone (Risperdal) and aripiprazole (Abilify) |