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The Digestive System
Chapter 19
Term | Definition |
---|---|
gastrointestinal (GI) tract | A continuous tube that extends from the mouth to the anus |
accessory digestive organs | Teeth,tongue, salivary glands, liver, gallbladder, and pancreas |
ingestion | This process involves taking foods and liquids into the mouth (Eating) |
secretion | Each day, cells within the walls of the GI tract and accessory organs secrete a total of about 7 liters of water, acid, buffers, and enzymes into the lumen of the tract |
mixing and propulsion | alternating contraction and relaxation of smooth muscle in the walls of the GI tract mix food and secretions and propel them toward the anus. (Motility) |
digestion | Mechanical and chemical processes break down ingested food into small molecules |
mechanical digestion | the teeth cut and grind food before it is swallowed, and then smooth muscles of the stomach and small intestine churn the food |
chemical digestion | the large carbohydrate, lipid, protein, and nucleic acid molecules in food are broken down into smaller molecules by digestive enzymes |
absorption | the entrance of ingested and secreted fluids, ions, and small molecules that are products of digestion into the epithelial cells lining the lumen of the GI tract |
defecation | wastes, indigestible substances, bacteria, and cells shed from lining of the GI tract, and digested materials that were not absorbed leaved the body through the anus |
mucosa, submucosa, muscularis, and serosa | four layers of the GI tract |
mucosa | A layer of epithelium, areolar connective tissue (propia), smooth muscle (lamina muscularis mucosae) that increases surface area for digestion and absorption and protects GI against pathogens |
submucosa | Areolar connective tissue that binds the mucosa and muscularis |
muscularis | skeletal muscle that forms the external anal sphincter, mouth, pharynx, and upper esophagus |
serosa and peritoneum | membrane that secretes a slippery, watery fluid that allows the tract to glide easily against other organs |
greater omentum | drapes over the transverse colon and small intestine like a "fatty apron" |
mesentery | A part of the peritoneum that binds the small intestine to the posterior abdominal wall |
oral cavity | cheeks, hard and soft palates, and tongue |
hard palate | consists of the maxillae and palatine bones, forms most of the roof of the mouth |
soft palate | muscles in the mouth |
uvula | projections of the soft palate, prevents entry of food and liquids into the nasal cavity |
lingual frenulum | a fold of mucous membrane in the midline of the undersurface of the tongue, limits the movement of the tongue posteriorly |
papillae | projections on the upper surface and sides of the tongue |
parotid, submandibular, sublingual | 3 salivary glands |
parotid glands | located inferior and anterior to the ears between the skin and masseter muscle |
submandibular glands | found in the floor of the mouth |
sublingual glands | beneath the tongue and superior to the submandibular glands |
saliva | 99.5% water, 0.5% solutes. Water helps dissolve foods so they can be tasted and begins digestion. Solutes begin digestion of starches in the mouth |
salivary amylase | breaks down starch in the mouth |
salivation | secretion of saliva |
mastication | mechanical digestion consisting of chewing |
bolus | end product of mastication |
pharynx | a funnel-shaped tube that is composed of skeletal muscle and lined by mucous membrane |
esophagus | a muscular tube lined with stratified squamous epithelium, transports food to the stomach and secretes mucus |
upper esophageal sphincter and lower esophageal spincter | 2 sphincters at the end of the esophagus |
upper esophageal sphincter | regulates movement of food from the pharynx into the esophagus |
lower esophageal sphincter | regulates movement of food from the esophagus to the stomach |
voluntary, pharyngeal, and esophageal | 3 stages of swallowing |
voluntary stage | bolus is forced to the back of the mouth cavity and into the oropharynx by the movement of the tongue |
pharyngeal stage | breathing is temporarily interrupted when the soft palate and uvula move upward to close off the nasopharynx and the epiglottis seals of the larynx |
esophageal stage | food is pushed through the esophagus by peristalsis |
peristalsis | muscular contractions along the esophagus |
stomach | mixing chamber and holding reservoir |
rugae | large folds of the mucosa |
mucous neck cells | secrete mucus |
chief cells | secrete pepsinogen |
pepsinogen | inactive form of pepsin |
parietal cells | produce hydrochloric acid which kills microbes and converts pepsinogen into pepsin |
gastric juices | the secretions of the mucous, chief, and parietal cells |
G cells | secrete the hormone gastrin |
mixing waves | gentle, rippling peristaltic movements of the muscularis |
chyme | bolus mixed with gastric juices |
gastric emptying | mixing wave forces a small amount of chyme through the the partially closed pyloric sphincter into the duodenum |
pancreatic duct | secretions pass from the the pancreas to the duodenum; unites the common bile duct from the liver and gallbladder, forming a common duct to the duodenum |
acini | pancreatic cells arranged in clusters, exocrine |
pancreatic juice | cells within acini secrete a mixture of fluid and digestive enzymes, contains water, salt, sodium bicarbonate, and enzymes |
pancreatic islets | 1% of the other pancreatic cells, endocrine. Secrete glucagen, insulin, somastatin, and pancreatic polypeptide |
pancreatic amylase | breaks down starch in pancreas |
trypsin, chymotrypsin, and carboxypeptidase | protein-digesting enzymes |
pancreatic lipase | digests tryglycerides |
ribonuclease and deoxyribonuclease | digests nucleic acids |
enterokinase | activated form of trypsin |
liver | weighs 1.4 kgs and is the second largest organ in the body |
gallbladder | pear-shaped sac that hangs from the lower front margin of the liver |
lobules | units of the liver |
hepatocytes | specialized cells that make up lobules |
sinosoids | highly permeable capillaries |
emuslification | the breakdown of large lipid globules into a suspension of small lipid globules, and absorption of lipids following their digestion |
bilirubin | principal bile pigment |
absorptive cells | found in the small intestine, contain microvilli and digest and absorb nutrients in small intestinal chyme |
s cells, CCK cells, and K cells | secrete hormones into the bloodstream such as secretin, cholecystokinin (CCK), and glucose-dependent insulinotropic peptide (GIP) |
duodenal glands | secrete an alkaline mucus |
circular folds | permanent ridges of the mucosa and submucosa that enhances absorption by increasing surface area |
villi | fingerlike projections of the mucosa |
lacteal | lymphatic capillary |
microvilli | tiny projections of the plasma membrane |
intestinal juice | secreted by the intestinal glands, contains mucus, alkaline |
segmentations | localized contractions that slosh chyme back and forth |
maltase | splits maltose into two molecules of glucose |
sucrase | breaks sucrose into a molecule of glucose and a molecule of fructose |
lactase | digests lactose into a molecule of glucose and a molecule of galactose |
peptidases | enzymes produced by absorptive cells that line the villi |
micelles | tiny droplets that include some bile salt molecules along with the long chain fatty acids, monoglycerides, cholesterol, and other dietary lipids |
chylomicrons | large spherical particles that are coated with proteins |
mass peristalsis | a strong peristaltic wave that begins in the middle of the colon and drives the colonic contents into the rectum |
defecation reflex | result of mass peristalsis |
cephalic phase | smell, sight, sound, or thought of food activates neural centers in the brain, leading to salivation |
gastric phase | gastrin is released |
intestinal phase | slows digestion |