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Anti-Coags
Anti-Coagulants
Question | Answer |
---|---|
given to prevent formation of new clots and extension of clots already present. Does not _________ clots | Anti-Coagulants, dissolve |
main adverse effect of anti-coagulants is _______ | bleeding |
Anti-Coagulant not given orally | Heparin |
Antidote for Heparin | Protamine sulfate |
manages DVT, PE, and thrombophlebitis | Heparin |
drug of choice during pregnancy and lactation | Heparin |
Anti-Coagulant, Heparin are contraindicated in | GI ulcerations, IC bleeding, severe kidney or liver disease, severe hypertension |
short duration and frquent need to administer this drug are disadvantages | Heparin |
parenteral injection and local tissue reaction at injection sites are disadvantages of this drug | heparin |
Labs monitored: aPPT | Heparin |
Can be given SQ or IV drip | Heparin |
injected SQ and don't need to worry about close monitoring of labs bc they are used to keep coagulation time high | LMWH |
Based on child's weight | Heparin |
Most common ORAL anti-coag | Warfarin |
antidote for this anti-coag is V-K | Warfarin |
Acts in the liver to prevent synthesis of V-K clotting factors | Warfarin |
anticoagulant effects do not occur for 3-5 days after warfarin is started bc clotting factors already in the blood follow their normal pathway of elimination | Warfarin |
most useful in long-term prevention or management of venous thromoembolic disorders | Warfarin |
Contraindicated in Pregnancy | Warfarin |
Monitor PT and INR | Warfarin |
adverse effects are dermatitis, diarrhea, and alopecia | Warfarin |