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3312 #3

Cardiovascular Drugs- Antidysrhythmics

QuestionAnswer
agents that alter the heart's electrical conduction system are known as antidysrhythmics
drugs that are used to treat or prevent abnormal cardiac rates and/or rhythms antidysrhythmics
3 goals of antidysrhythmics are: 1. suppress or treat dysrhythmias 2. prevent or relieve symptoms 3. prolong survival
T or F Antidysrhythmics are used to potentially prolong life True
heart's ability to generate an electrical impulse is known as automaticity
movement of sodium and calcium ions into the cell, and movement of potassium out of the cell is known as initiation of electrical impulse
period of decreased excitability is known as refractory period
Dysrhythmia from SA node is called sinus dysrhythmia
dysrhythmia from AV node is called nodal dysrhythmia
dysrhythmia from atrium is called atrial dysrhythmia
dysrhythmia from ventricles is called ventricular dysrhthmia
A main concern with dysrhythmias is decreased cardiac output
T or F An action of antidysrhythmics is to increase aut0maticity False- an action of antidyysrhythmics is to decrease automaticity
T or F An action of antidysrhythmics is to slow conduction of electrical impulses True
T or F An action of antidysrhythmics is to prolong refractory period True
3 Actions of Antidysrhythmics are: 1. reduce automaticity 2. slow conduction of electrical impulses 3. prolong refractory period
T or F worsening of existing dysrhythmias is a potential general side effect or adverse effect True
T or F New dysrhythmias will not occur as a result of antidysrhythmic use False- new dysrhythmia formation is an adverse/general side effect of antidysrhythmic use
T or F Heart failure can be a general/adverse side effect of antidysrhythmic use True
T or F Hypertension is a general/adverse side effect of antidysrhythmic use False- hypotension is a general/adverse side effect of antidysrhythmic use
T or F fatigue is a general/adverse side effect of antidysrhythmic use True
5 General/Adverse Side effects are: 1. worsening or existing dysrhythmias 2. New dysrhythmias 3. heart failure 4. hypotension 5. fatigue
4 Classifications of Antidysrhythmics: 1. Class 1: Sodium-channel blockers; 1A, 1B, 1C 2. Class 2: beta-adrenergic blockers 3. potassium channel blockers 4. calcium channel blockers
Classification of antidysrhythmic that prevents NA+ influx into myocardium Class 1A Sodium Channel Blocker
3 Mechanisms of Class 1A Sodium Channel Blockers (qunindine) are: 1. reduces automaticity 2. slows conduction 3. prolongs refractory period
Example of Class 1A Sodium Channel Blocker is quinidine
Unique features of Class 1A Sodium Channel Blocker cinchonism- diarrhea
2 Mechanisms of Class 1B Sodium Channel Blockers (lidocaine) 1. decreases ventricular automaticity 2. selective depression of ectopic pacemakers
lidocaine falls under which Sodium Channel Blocker Class 1B
quinidine falls under which sodium Channel Blocker Class 1A
tamborcor falls under which Sodium Channel Blocker Class 1C
propranolol falls under which class of antidysrhythmics Class 2: Beta Adrenergic Blockers
unique features of Class 1B Sodium Channel Blockers include: 1. CNS stimulation or depression (dose-dependent)
Mechanism of Class 1C Sodium Channel Blockers (flecainide) greatly decreases ventricular conduction
flecainide is an example of which class of antidysrhythmic Class 1C Sodium Channel Blocker
unique features of Class 1C Sodium Channel Blockers 1. reserved for LIFE-THREATENING ventricular dysrhythmias that do not respond to safer drugs
unique features of Class 1C Sodium Channel Blockers 1. reserved for LIFE-THREATENING ventricular dysrhythmias that do not respond to safer drugs
mechanisms of Class 2 Beta Adrenergic Blocker (propranolol) 1. prevent adrenergic stimulation 2. myocardial depresion
propranolol is an example of which type of antidysrhythmic Class 2 Beta Adrenergic Blockers
Unique features of Class 2 Beta Adrenergic Blockers (propranolol) 1. activity intolerance 2. hypoglyemia (masks symptoms) 3. risk of bronchoconstriction
What is unique about flecainide it is a last resort drug
All beta blockers end in? olol
How do Class 2 Beta Adrenergic Blockers mas symptoms of hypoglycemia symptoms of hypoglycemia occur due to stimulation of SNS, these meds block this ability to stimulate SNS, thus masking symptoms
Mechanisms of Class 3 Potassium Channel Blockers (amiodarone) 1. inhibits adrenergic stimulation (prolongs refractory period) 2. slows SA, AF conduction
amiodarone is an example of what type of antidysrhythmic Class 3 Potassium Channel Blocker
unique features of Class 3 Potassium Channel Blockers (amiodarone) are 1. used in ER situations, given IV 2. limited use PO; serious adverse effects 3. long half life
A serious adverse effect of Class 3 Potassium Channel Blockers (amiodarone) is pulmonary fibrosis
what is unique about Class 3 Potassium Channel Blockers in relation to pharmacist pharmacist must counsel pt before giving
mechanisms of Class 4 Calcium Channel Blockers (verapamil) 1. improves coronary blood flow by relaxing smooth muscle 2. slows SA and AV conduction
verapamil is an example of which class of antidysrhythmic Class 4 Calcium Channel Blockers
unique features of Class 4 Calcium Channel Blockers effect on heart rate and blood pressure
contraindication for antidysrhythmics heart block
Interactions with antidysrhythmics would include any other drugs that affect ___ 1. contractility 2. cardiac rate and/or rhythm 3. blood pressure
As a nurse, you assess which 6 things for a pt on antidysrhythmics 1. apical heart rate and rhythm 2. B/P 3. peripheral edema 4. activity intolerance 5. respiratory status 6. ECG
Alternative Treatment for very fast heart rate: carotid sinus massage valsalva maneuver
Alternative Treatment for very slow heart rate: pacemaker
non-allopathic drugs are: omega 3 fatty acids- unclear or conflicting evidence mistletoe- used in other countries for heart palpatations; no scientific evidence
deficient knowledge of self care while taking antidysrhythmic drugs r/t inadequate teaching interventions? 1. activity intolerance 2. take in regular spaced intervals 3. suppresses CNS response 4. stay away from caffeine 5. the purpose is to keep HR down 60-65
Created by: Black88cat
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