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Inotropics
Heart Failure Drugs
Question | Answer |
---|---|
Digitalis: digixon (Lanoxin) | Action: Increases Ca into cells to increase myocardial contraction Features: Hypokalemia increases risk of toxicity; contraindicated with heart block |
Phoshodiesterase Inhibitors: Inocor | Action: Increases cAMP to increase myocardial contraction Features: Used for short term treatment AE: low BP and platelets |
ACE Inhibitors: Capoten | Action: Decreases cardiac workload by suppressing RAA and improves perfusion Features: 1st line with diuretics; can cause chronic cough |
Human natriuretic Peptide b-type : Natrecor | Action: Decreases cardiac workload by suppressing RAA Features: Can cause hypotension and incompatible with most IV infusions |
Endothelin receptor antagonist: Tracleer | Relax blood vessels to reduce cardiac workload |
Non-allopathic: CoEnzyme Q10 | Decrease complications and hospitalizations r/t heart failure |