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Gen Antimicrobial

Pharm 3312 for final

QuestionAnswer
What are the mechanisms of action that antimicrobials use to break down bactera? 1) Inhibits protein synthesis 2) decreases metabolism growth and reproduction 3) impairs cell wall 4) disrupts cell membrane.
What are examples of natural resistance to antimicrobial? Natural - 1)Enzymes destroy drug 2)Empermeable cell wallblocks drug entry 3)Cell pump expels drug
What are examples of acquired resistance to antimicrobial? 1)Survival of the fittest 2)Genetic mutation 3)Genetic transfer 4)Altered metabolic pathways
Resistance is classified into what two categories? Natural – referring to protective characteristics thatare present before drug exposureAcquired – referring to characteristics that aredeveloped after exposure to a drug
Drug-resistant organisms encouraged by: 1)Widespread antimicrobial use 2)Interrupted/inadequatetreatment 3)Type of bacteria 4)Type of infection 5)Condition of host 6)Location/setting of care.
What does DOT stand for? Directly observed therapy. Used for non-compliant TB patients.
Identify types of adverse effects common to anti-microbial drugs. 1)Allergic reaction 2)Superinfection 3) Photosensitivity 4)Direct toxicity.
Created by: krosen75
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