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Hema. WBC Variations
Hematology Variations in WBCs Morphology
Question | Answer |
---|---|
Cells showing a variations in morphology in an abnormal response to a stimulus are... | Pathological |
Cells show variation in morphology but no physiological impairment results. | Non-Pathological |
Cells show variation in morphology as a normal body response to invasion by a bacteria or virus. | Reactive |
Neutrophils with more than 6 lobes are defined as | HYPERsegmented |
Why do hypersegs form? | DNA production defect slows production down & the nucleus forms many lobes. |
True or False Hypersegmented Neutrophilic cell size remains the same with hypersegmentation. | False. They can become larger than 15 microns |
The cytoplasm of Hypersegmented neutrophils is less funtional. True or False | False. They cytoplasm is normal in appearance and is still phagocytic. |
Barr bodies are significant only when? | In diseases of chromosomal abnormailities. |
Disease conditions of hypersegmented neutrophils include | Megaloblastic anemias (Folic acid deficency, or pernicious anemia), cancer therapy, chronic infections. |