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Pharmacology Study
Pharmacologic Principles
Question | Answer |
---|---|
The highest level a drug reaches in the body. | Peak Concentration |
The strength of the attraction between a drug and receptor | Affinity |
Decreased responsiveness as a result of repeated drug administration | Tolerance |
Lipid soluble drug | Lipophilic |
The study of drugs in humans | Clinical Pharmacology |
Immune system response | Allergic reaction |
Study of drugs and their interactions with living organisms | Pharmacology |
The moving of drugs and their metabolites out of the body | Excretion |
The body has adapted to long term drug exposure in such a way that an abstinence syndrome results if the drug is stopped | Physical Dependence |
The ratio of the 50% lethal dose to the 50% effective dose measures drug safety | Therapeutic index |
Adverse reaction caused by over dosing | Toxicity |
Using drugs to diagnose, prevent, or treat disease or prevention of pregnancy | Therapeutics |
Medicines and other chemicals that can cause birth defects | teratogens |
any chemical that can affect living processes | drug |
antagonists that bind irreversibly to receptors | noncompetitive antagonists |
molecules that activate receptors | agonists |
molecules that prevent receptor activation by endogenous regulatory molecules and drugs | antagonists |
the plasma level at which toxic effects begin | toxic concentration |
an uncommon drug response resulting from a genetic predisposition | idosyncratic effect |
The ability of certain medications and environmental chemicals to cause cancers | carcinogenic effect |
the largest effect that a drug can produce | maximal efficacy |