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Car/Pul Final Exam
SPC Cardiopulmonary Physiology Final Exam Unit 4 Review
Question | Answer |
---|---|
High V/Q Ratio & Location? | 4/4=1.0 Apical Region Of Upper Right Lung |
Low V/Q Ration & Location? | 3/5=0.6 Basal Region Of Lower Right Lung |
Disease/Disorders of High V/Q? | (Deadspace) 1. Pulmonary Emboli 2. Circulatory Shock |
Disease/Disorders of Low V/Q? | (Shunt) 1. Atelectasis 2. Pulmonary Edema 3. Pneumonia |
Fick's Law: Gas diffusion across a tissue (A/C) membrane is DIRECTLY PROPOSTIONAL to what? | 1. Membrane Surface Area 2. Gas Pressure Gradient 3. Gas's Pressure Coefficient |
Fick's Law: Gas diffusion across a tissue (A/C) membrane is INVERSELY PROPOSTIONAL to what? | 1. Membrane Thickness |
Hemoglobin "A" is protein base composed of what? | 1. 2 Alpha Polypeptide Chains 2. 2 Beta Polypeptide Chains 3. 4 Heme (Iron) Groups (each heme combines w/ an O2 molecule) |
What is P50? | The partial pressure required to saturate the Hb to a 50% level |
Normal P50? | 27mmHg |
Decrease P50? | <20mmHg Left Shift: (Load) O2 Loading Easier in Lung O2 Unloading Harder in Tissue |
Increase P50? | >35mmHg Right Shift: (Release) O2 Loading is Harder in Lung O2 Unloading is Easier in Tissue |
P50 Left Shift Factors? | Increase pH (Alkalemia) 1. Decrease CO2 2. Hypothermia 3. Decrease 2,3 DPG |
P50 Right Shift Factors? | Decrease pH (Acidemia) 1. Increase CO2 2. Hyperthermia 3. Increase 2,3 DPG |
What are the 3 altered Hemoglobin's? | 1. Methemoglobin 2. Carboxyhemoglobin 3. Fetal Hemoglobin |
What is Methemoglobin (MHb)? | A congenital or chemically induced alteration of the HEME portion of Hb: Decrease P50 |
What is Carboxyhemoglobin (HbCO)? | Carbon Monoxide (CO) poisoning or cigarette smoking: Decrease P50 |
What is Fetal Hemoglobin (HbF)? | Seen in fetus and neonate, converted to HbA by 6mo. Altered 2,3 DPG binding noted with HbF |
Formula for DO2? | C.O. x (CaO2 x 10) = DO2 |
Normal Value for DO2? | 1000ml/min |
Formula for O2 Consumption? | C.O. (Ca-vO2 x 10) = O2 Consumption |
Normal Value for O2 Consumption? | 250ml/min |
4 factors that increase O2 Consumption? | 1. Exercise 2. Seizures 3. Shivering 4. Hyperthermia |
3 factors that decrease O2 Consumption? | 1. Peripheral Shunting 2. Cyanide Poisoning 3. Hypothermia |
Normal Value for Ca-vO2? | 20-15=5ml O2/dL |
6 factors that increase Ca-vO2? | 1. Decrease C.O. 2. Increase O2 Consumption 3. Exercise 4. Seizures 5. Shivering 6. Hyperthermia |
5 factors that decrease Ca-vO2? | 1. Increase C.O. 2. Decrease O2 Consumption 3. Peripheral Shunting 4. Cyanide Poisoning 5. Hypothermia |
Formula for O2ER? | (CaO2-CvO2)/CaO2) = O2ER |
6 factors that increase O2ER? | 1. Decrease C.O. 2. Increase O2 Consumption 3. Exercise 4. Seizures 5. Shivering 6. Hyperthermia |
5 factors that decrease O2ER? | 1. Increase C.O. 2. Decrease O2 Consumption 3. Peripheral Shunting 4. Cyanide Poisoning 5. Hypothermia |
Formula for Qs/Qt? | (CcO2 - CaO2)/(CcO2 - CvO2) = Qs/Qt |
Normal Qs/Qt? | <10% |
Mild Qs/Qt? | 10-20% |
Moderate Qs/Qt? | 20-30% |
Severe Qs/Qt? | >30% |