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Oncology
Med Surg 3 Exam 5
Question | Answer |
---|---|
Most leukemia occurs in children. T/F | False. 70% occurs in people > 60 years old. |
lymphoid: | stem cells that produce lymphocytes |
myeloid: | stem cells that produce non-lymphoid |
Most likely patient of: AML | children adults |
Most likely patient of: ALL | children "childhood cancer" but can see in adults |
Most likely patient of: CML | adults |
Most likely patient of: CLL | 55+ |
ANT | anemia, neutropenia, thrombocytopenia |
Which cancer? s/s: fever, infection, fatigue, risk for bleeding, LYMPHADENOPATHY, spleenomegaly (rare) | AML |
NADIR | 7-10 days after chemo |
which cancer has the phases 1 (chronic) 2 (transformation) 3 (accelerated)? | CML |
Which cancer? s/s: fatigue, malaise, anorexia, weight loss, dyspnea, confusion, SPLEENOMEGALY, lymphadenopathy (rare) | CML |
How do you diagnose CML? | BCR-ABL gene, BMB, CBC diff |
"Philadelphia chromosome" | BCR-ABL gene |
PO med for CML | Gleevac |
Which cancer? s/s: bone pain, lymphadenopathy, spleenomegaly, headache | ALL |
what is the treatment for ALL? | combo chemo, intrathecal chemo, stem cell transplant |
The B lymphocytes are affected in which cancer? | CLL |
which cancer? s/s: increased lymphocytes, lymphadenopathy, spleeomegaly, b symptoms, viral infection | CLL |
disorder of myeloid stem cells | myleodysplastic syndrome |
dysplasia of RBC | myelodysplastic syndrome |
which cancer? s/s: fatigue, BONE MARROW FAILURE, | myelodysplastic syndrome |
bone marrow treatment is the only cure | myelodysplastic syndrome |
reed-sternberg cells | hodgkin lymphoma |
risk factors: virus, immunosuppressive therapy, agent orange | hodgkin non-hodgkin |
which cancer? s/s: lymphadenopathy (cervical, mediastinal, supraclavicular), puritus, B symptoms, infections (herpes zoster) | hodgkin lymphoma |
lymphoma staging: I | local; one node region |
lymphoma staging: II | two node regions above diaphragm same side |
lymphoma staging: III | two node regions above below diaphragm |
lymphoma staging: IV | everywhere; organs |
what is the treatment goal for hodkins lymphoma | cure |
which cancer? lymphoid tissue is infiltrated with malignant cells | Non-hodgkins |
what is the most common NHL? | B cell (aggressive) |
which cancer? s/s: variable, enlarged lymphnodes, B symptoms, CNS | NHL |
what does RCHOP treat? | NHL |
RCHOP stands for: | Rituxan Cytoxan Hydroxydanumycin Onvovin Prednisolone |
cancer of the plasma cells | multiple myeloma |
which cancer? s/s: bone pain (back/ribs), bone breakdown, increase Ca+ (thirsty, dehydrated, confused), renal failure (M protein damages tubules), bone marrow depression | multiple myeloma |
M protein in blood M protein in urin (Bentz-Jones) CRAB | multiple myeloma |
where do the stem cells come from for a transplant? | peripheral blood stem cells umbillical cord newborns |
allogenic | donor other than patient |
syngenic | transplant from identical twin |
autologus | patient own cells |
myloablative | inpatient; high chemotherapy wipe out bone marrow |
non-myloablative | mini-transplant; doesn't destroy all cells |
how long does it take for patient to begin making own cells? | 2-4 weeks |
which 911? s/s: SOB, edema, dysphagia, dilated veins on chest | SVC syndrome |
which 911? s/s: back pain, edema, numbness, motor loss | spinal cord compression |
which 911? s/s: fatigue, confusion, dysrhythmmia, constipation, dehydration | hypercalcemia |
which 911? s/s: fatigue, weakness, level of conciousness, increase K+, increased P, decreased Ca+, acute renal failure, dysrhythmia, seizures | tumor lysis syndrome |
mass cell destruction | tumor lysis syndrome |
most common cancer in this 911 (hypercalcemia) | breast, lung, renal, myeloma |