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patho1
Question | Answer |
---|---|
What is a prognosis? | the LIKELY cause of a medical condition |
What is the definition of sequelae? | the consequences of a particular condition or therapeutic intervention |
What are the 3 levels of disease prevention and a definition of each. | primary (prevent transmission - immunizations), secondary (screening and testing - mammograms), tertiary (prevent complications of a disease that already exists - taking a baby aspirin per day) |
What is epidemiology? | the study of patterns of disease in large groups of people |
Turner's Syndrome is missing the (blank) chromosome? | X |
First line of tissue defence? | barriers, mucous membranes, tears, saliva |
Second line of tissue defence? | acute inflammatory response |
5 major local signs and symptoms of inflammation | 1) redness 2) swelling 3)heat 4)pain 5)loss of function |
Definition of autoimmunity? | attacks own tissues |
Deinition of alloimmunity? | rejection of other person's tissues (transplant, blood transfusion) |
Gammaglobulin therapy, transplantation/transfusion, and gene therapy are all treatments for...? | immunodeficientcies |
Hypogammaglobulinemia? | low levels of immunoglobulins |
Agammaglobulinemia? | No circulating immunoglobulins |
Bruton agammaglobulinemia? | caused by blockage of development of mature B-cells in bnursal equivalent tissue (otitus media, sore throat) |
DiGeorge Syndrome? | abnormal facial development, low ears, wide set eyes, short upper lip. Caused by partial or complete absence of T-cell immunity |
Type 1 Hypersensitivity? | allergy, IgE mediated, against enviro antigens, IgE binds to receptors on surface of mast cells, histamine release |
Type 2 Hypersensitivity? | tissue specific. eg.-hemolytic disease of the newborn Rh+, jaundice |
Type 3 Hypersensitivity? | immune complex mediated. eg.-serum sickness (immune complexes formed in blood and deposited in tissues, anthus reaction |
Type 4 Hypersensitivity? | does not involve antibody. eg.- acute graph rejection, skin test for TB, contact allergic reaction, and autoimmune disease |
What does SLE stand for? | systemic lupus erythmatosus. clinical manifestations --> arthritis, butterfly facial rash, renal disease, cv disease, etc |
Blood type AB is...? | universal recipient |
Blood type O is...? | universal donor |
Water accounts for approx. what percent of a normal adults body weight? | 60% |
What hormone is stimulated by a drop of BP or an increase in serum osmolarity? | ADH |
What hormone promotes the retension of Na+? | aldosterone |
What promotes fluid loss when the atria are stretched by high fluid volume or BP? | ANP (atrial natriuretic peptide) |
What promotes the retention of sodium and water in times of stress? | glucocorticoids |
What stimulates ADH and aldosterone release? | thirst! |
Cerebralspinal fluid, GI tract fluid, and fluid found int the pleural, synovial, and peritoneal spaces make up which compartment of fluid? | transcellular compartment |
What is the most prevalent cation found in the EXTRACELLULAR fluid compartment? | Na+ |
What is the most prevalent anion found int eh EXTRACELLULAR fluid compartment? | Cl- |
Waht is the most prevalent cation found in the INTRACELLULAR fluid compartment? | K+ |
What is the most prevalent anion found in the INTRACELLULAR fluid compartment? | PO4- |
Which electrolyte maintains excitability of neurons, cardiac muscle cells, and sensory receptors? | K+ |
Which electrolyte is an importnat requirement in the proper functioning of the Na+/K- pump? | Mg++ |
Which electrolyte is regulated by the kidneys under the influence of aldosterone? | Na+ |
Which electrolyte is excreted by the kidneys in exchange for Na+ and H+ | K+ |
Which hormone increases levels of PTH while calcitonin decreses levels of this electrolyte? | Ca++ |
Which hormones levels are influenced indirectly by aldosterone and directly by bicarbonate concentration? | Cl- |
Which hormone is influneced directly by parathyroid hormone levels? | PO4-- |
Normal serum levels for Na+? | 135-145mEq/L |
Normal serum levels for K+? | 3.5-4.5mEq/L |
Normal serum levels for Ca++? | 1.8-2.3mEq/L |
Normal serum levels for Mg2++? | 1.7-2.6mEq/L |
Normal serum levels for Cl-? | 95-108mEq/L |
Normal serum levels for PO4--? | 4.5-5.5mEq/L |
Normal plasma pH is? | 7.35-7.45mEq/L |
Pedes have approx. how much body water content? | 75-80% |
What are some causes of excess Na+? | renal failure, decreased ADH, hyperatremia, hypervolemia |
What are some causes of a Na+ deficit? | profuse sweating, distilled H2O, vomiting, diarrhea, diuretic, burns |
To maintain the body's normal pH the H+ must be neutralized by buffers or excreted via the....? | lungs/kidneys |
The most important plasma buffering systems are the | carbonic acid-bicarbonate system and hemoglobin protien |
ABG stands for..? | arterial blood gases |
Metabolic acidosis is...? | depression of HCO3- or an increase in non-carbonic acids |
Metabolic alkalosis is...? | the elevation of HCO3- usually caused by an excessive loss of metabolic acids |