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Psych
Question | Answer |
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Side effects include muscular rigidity and cramping, a stiff or thick tongue with difficulty swallowing. usually occurs in the 1st week of treatment, in pt under 40yo, males, drugs involved Haloperidol & Thiothixene | Dystonia |
twisted head and neck | torticollis |
tightness in the entire body with the head back and an arched neck | opisthotonus |
eyes rolled back in a locked position | oculogyric crisis |
loss of coordination of muscles especially those of the extremities | ataxia |
what medications are used to treat Acute Dystonia | IM benztropine mesylate or IM/IV diphenhydramine |
intense need to move about | akathisia |
a potentially fatal idiosyncratic reaction to an antipsychotic drug. often occurs in the first 2 weeks of treatment or after a increase in dosage. | Neuroleptic malignant syndrome |
S/S rigidity, high fever, autonomic instability such as unstable BP, diaphoresis, pallor, delirium, and elevated levels of enzymes | NMS neuroleptic malignant syndrome |
TX immediate discontinuance of all antipsychotic medication and the institution of supportive medical care to treat dehydration and hyperthermia | NMS neuroleptic malignant syndrome |
S/S involuntary movement of the tongue, facial and neck muscles, upper/lower extremities. tongue thrusting & protruding, lip smacking, blinking, grimacing after it develops it is irreversible. Tx includes Atypical antipsychotic drugs | Tardive dyskinesia |
S/S stiff stooped posture, mask-like-facies, decreased arm swing, a shuffling, festinating gait (small steps), cogwheel rigidity (ratchet like movements of joints), drooling, tremor, bradycardia, pill rolling | pseudoparkinsonism |
ziprasidone is contraindicated in pt with a known HX of QT prolongation, recent MI, or uncompensated heart failure. it should not be used with other QT-prolonging drugs | FYI |
acute dystonia, pseudoparkinism, akathisia | extrapyramidal symptoms |
clients taking anticholinergic agents for EPS may have problems with anticholinergic side effects. Side effects usually decrease within 3-4 weeks but don't entirely remit | FYI |
this drug may cause agranulocytosis, which may not show up for 24 weeks after TX is started. It also causes pt to have a baseline WBC count & differential before initiation of TX and Q weekly for 6 months and 4 weeks after discontinuation | Clozapine (Atypical antipsychotic) |