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medications
labor & delivery
Question | Answer |
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Oxytocics: oxytocis - uterine stimulants | induction of labor (postterm pregnancy, PROM, preeclampsia) delivery of placenta (postpartum, miscarriage) mgmt. of postpartum hemorrhage. stress testing |
dinoprostone | a prostaglandin used to promote cervical ripening & to stimulate uterine contractions. complications: uterine tachysystole - monitor: VSs length, strength & duration of contractions. Assess fetal status. |
Methylergonovine | contracts the uterus & is used for emergency intervention for serious postpartum hemorrhage. complications: hypertensive crisis (headache, n/v, increased BP) |
oxytocics - complications | uterine rupture, uterine tachysytole, placental abruption, hyponatremia. RN consideration: monitor VSs, I&O, length, strength & duration of contractions, assess fetal status. avoid concurrent use w/MAOIs. CNS depressants increase effects. |
oxytocin contraindications/precautions | maternal factors: sepsis, an unripe cervic, active genital herpes, HX of multiple biths, uterine surgery. fetal factors: imm lungs, cephalopelvic disproportion, fetal malprstn, prolapsd umbl cord, fetal distrss, plactl abnormalities, threatened spontane |
dinoprostone contraindications/precautions | cesarean birth, fetal distress, vaginal bleeding. use w/caution w/maternal hx of hypotension, htn, athsma. avoid concurrent use w/other oxytocics increase effects, monitor VSs, uterine activity, fetal status. |
methylergonovine contraindications/precautions | HTN, preeclampsia, asthma, cardiac disease use only after delivery & not during labor. caution: w/maternal HX of severe renal or hepatic disease, DM, sepsis, epilepsy. avoid concurrent use w/vasopressors, ergots increase effects. monitor VSs. |
nursing administration | 1 milliunits/min every 30 to 60 min. monitor VSs 30 to 60 min. uterine contraction every 15 min. during 1st. stage of labor. every 5 min during 2nd. stage of labor, uterine tachysystole, FHR & rhythm |
tocolytics medications | Terbutaline, hydroxyprogesterone caproate, nifedipine, indomethacin, magnesium. delays delivery for 48 hours to allow maximum benefit of glucocorticoids to decrease the incidence of RDS. |
terbutaline | monitor VSs, blood glucose, potassium levels report A/Es. have propranolol available hypersensitivity: caution w/chronic/active hepatic disease, renal disease. interactions w/MAOIs, green tea, decrease effect of beta-blockers, |
hydroxyprogresterone caproate | inject site reactions: monitor for pain, swelling, itching & appearance of hives. caution: uncontrolled HTN, liver disese, hx of thrombosis, breast cancer. |
nifedipine | hypotsn, headache, dizziness, nausea . caution w/hypotsn, hepatic/ renal disease or acute MI. hypersensitivity: avoid conct use w/magnesium sulfate or terbutaline. avoid using w/grapefruit juice, ginkgo biloba, ginseng, melatonin, St. John's Wort. |
Indomethacin | Matl: n/v heartburn, GI bleed, thrombocytopenia Fetal: neona-tal pulmonary HTN, oligohydramnios. caution: GI bleeding, hyper-sensitivity, use <32wks. gest. for 48 hrs. avoid NSAIDs, alcohol, salicylates, mtr toxicity blurred vision, ringing in ears). |
magnesium sulfate | monitor serum magnesium level, limit fluids to 125ml/hr have calcium gluconate available. d/c infusion w/intolerable A/Es avoid concurrent use w/nifedipine. increase antihypertensives, calcium blockers, neuromuscular blockers, decrease effect digoxin |
glucocorticoid meds: adm bet/n 24 & 34 wks of gestation. betamethasone 12mg IM for 2 doses 24hrs. apart dexamethasone 6mg IM for 4 doses 12 hours apart. | releases enzymes that produce & release lung surfactant to stimulate lung maturity in a fetus. |
opioids: fentanyl, butorphanol, nalbuphine | adm w/in provide pain relief w/out causing respiratory depression in mother & fetus. adm IM or IV or IV during labor. complications: dry mouth, n/v, neonatal depression, tachycardia, hypotension, decreased FHR variability, sedation |
opioids contraindications/precautions | delivery w/in 1 to 4 hr of adm. if opioid is gven too soon, it can delay progression of labor. if given too late, it can depress neonatal resprations |