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IMMUNE FUNCTION
Ch. 35
Term | Definition |
---|---|
Agglutination | clumping effect occurring when Antibody acts as cross link btw 2 antigens |
Antibody | protein developed by body in response to & interacting w/ specific antigen |
Antigen | induces the production of antibodies |
Apoptosis | programmed cell death that results from the digestion of deoxyribonucleic acid by end nucleases |
B cells | produce humoral immune response |
Cellular Immune Response | immune system's 3rd line of defense, attack of pathogens by T cells |
Complement | series of enzymatic proteins in the serum that when activated destroy bacteria & other cells |
Cytokines | term for nonantibody proteins that act as intercellular mediators, as in the generation of immune response |
CYTOTOXIC T cells | lymphocytes that lyse cells infected with virus, play a role in graft rejection |
Epitope | component of antigen molecule that functions as an antigenetic determinant by permitting the attachment of certain antibodies |
Genetic Engineering | emerging technology designed to enable replacement of certain antibodies |
HELPER T cells | lymphocytes that attack foreign invaders (antigens) directly |
Humoral Immune Response | coordinated response of components of immune sys to a foreign agent or organism |
Immune System | collection of organs, cells, tissues, & molecules that mediate the immune response |
Immunity | body's specific protective response to a foreign agent or organism |
resistance to disease, specifically infectious disease | Immunity |
Immunopathology | study of diseases resulting in dysfunctions w/in immune sys |
Immunoregulation | complex sys of checks & balance that regulates or controls immune responses |
Interferons | proteins formed when cells are exposed to viral or foreign agents |
Capable of activating other components of immune sys | Interferons |
Lymphokines | substances released by sensitized lymphocytes when they come in contact with specific antigens |
Memory Cells | recognize antigens from previous exposure & mount an immune response |
Natural Killer (NK) Cells | LYMPHOCYTES that defend against microorganisms & malignant cells |
Null Lymphocytes | destroy antigens already coated with antibody |
Opsonization | coating of antigen-antibody molecules with a sticky substance to facilitate phagocytosis |
Phagocytic Cells | engulf , ingest, & destroy foreign bodies or toxins |
Phagocytic Immune Response | immune system's first line of defense, involving WBCs that can ingest foreign particles |
Stem Cells | precursors of all blood cells, primarily in BONE MARROW |
Suppressor T Cells | LYMPHOCYTES decrease B-cell activity to level that immune sys is compatible with life |
T Cells | produce cellular response |
Autoimmunity | normal protective immune response turns agst or attacks the body = tissue damage |
Hypersensitivity | inappropriate or exaggerated response to specific antigens |
Gammopathies | overproduction of immunoglobulins |
Primary Immune Deficiency | improper development of immune cells or tissues; congenital or inherited |
Secondary Immune Deficiency | some interference with already developed immune sys, acquired later in life |