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Immune system,Inflam

Immune system,Inflammation, and War on Bugs

QuestionAnswer
what is Second Line of Defense Imflammation
what are Cardinal signs for imflammation Redness ; Swelling ; Heat ; Pain
Symptoms are the result of the release of chemicals from what? • Injured endothelial cells ; • Mast cells ; • WBC macrophages & neutrophils
what cell release Histamine? Histamine is released from mast cells, and damaged cells. Histamine is a potent vasodilator.
what result when Tumor necrosis factor stimulates ? vasodilation, coagulation.
what result when Leukotrienes, protaglandins stimulates? bronchial constriction, vasodilation
what response when Complemen Plasma Proteins ystems Stimulated Immediate vasodilation, increased vascular permeability
what response when Kinin Stimulated Long term inflammatory response Clotting proteins
what is the most worry when systemic inflammatory response or other injury? Clotting system
what ions (mineral) are needed for clotting Ca and K
What are Systemic Inflammatory Response ? Temperature > 38C or < 36C; > 100.4F or < 98.6F Heart rate > 90 beats per minute Respiratory rate > 20 breaths per min. or PaCO2 < 32mmHG ; WBCs > 12000 cells/cubic millimeter, < 4000 cells/cubic millimeter, or > 10% bands
what are Early Signs of Sepsis? Hypotension; Tachycardia ; Tachypnia; Febrile ;O2 sat ; Change in LOC, Malaise
What is band in WBC? immature neutrophils have banded nuclei.
phagocytic cells to arrive at the site of injury Neutrophilsp
how long Neutrophils are present before macrophages arrive? 72 hrs
when do Basophils appear or circulate? tissue damage ; Release histamine and heparin in areas of tissue damage
when do Eosinphils increase in circulation? Increase with allergic reactions and parasite infestation
what do Eosinphils do? Release an antivasoactive factor.
what do Basophils do? Release histamine and heparin in areas of tissue damage
what white cell becomes mast cell? Neutrophils ; Eosinophils ; Basophils Basophils
what white cell become Macrophages ? Monocytes
what is 3rd Line of Defense? Immune Response
what are 4 cases when the temp>100 is critical situation? pt with chemotheraly, neanate, brain injury; pt with transplant
Created by: tp667
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