Question
click below
click below
Question
Normal Size Small Size show me how
Cellular
Adv Patho ETSU 5016 NP
Question | Answer |
---|---|
Which cells have a nucleus and membrane enclosed organelles | Eukaryotic Cells |
Which cells are unicelluar without nucleus or organelles? | Prokaryotic Cells |
Which cells have cell membrane, cytoplasm, and genetic material (DNA) | All cells |
Which cells have mitochondria? | plant and animal cells |
What dictates what the cell will do and how it will do it? | DNA |
What is chromatin | Tangled form of DNA inside nuclear membrane |
When DNA is ready to divide, what do the chromatin form into? | Chromosomes |
Where are ribosomes created? | Nucleolus |
What do ribosomes synthesize? | proteins |
What is the structure that ribosomes attach to to form proteins? | Rough endoplasmic reticulum rER |
What is smooth endoplasmic reticulum sER | w/o ribosomes |
What is the function of the ER? | To release proteins in vesicles to the Golgi bodies |
What is the fx of the Golgi body | It reforms proteins so the body can use them and adds things like lipids/carbs |
What are lysosomes fx? | Take in damaged parts of cells and break down using enzymes |
What is fx of mitochondria | Cellular respiration and make ATP |
How does cell maintain shape? | The cytoskeleton is maintained via microfilaments and microtubules |
What is the only animal cell with a flagellum? | sperm cell |
As RBCs mature, what do they lose? | lysosomes |
As RBCs mature what do they produce? | hemoglobin |
As RBCs mature, they have small __________ bodies and enlarged___________? | Golgi, endoplasmic reticulum, lose mitochondria |
How much ATP is produced in aerobic respiration? | 36 ATP |
How much ATP produced in glycolysis? Anaerobic Energy Metabolism? | 2 ATP |
How much ATP in Krebs Cycle? Aerobic Energy Metabolism | 2 ATP |
How much ATP produced in Electron Transport Chain? | 32 ATP |
What is the chemical reaction formula in aerobic respiration? | C6h12O6 + 6O2 = 6CO2 + 6 H2O |
What occurs in glycolysis? | |
What occurs in the Krebs cycle? | |
Is glycolysis aerobic or anaerobic? | Anaerobic |
What is passive diffusion? | Molecules move randomly away from the area where they are most concentrated |
What is facilitated diffusion? | Mol diffuse across a membrane by passing through a protein |
What is Osmosis? | Diffusion of water mol |
What do receptor proteins do? | Enable cell communication by attaching to cell surface and open ion channel. Cause 2nd cell released in cell, turn on enzymes and stimulate transcription of genes in nucleus. |
Is resting membrane potential negative or positive? | Negative (inside cell) |
What changes cell to be more positive? | NA+ ions to diffuse in cell, depolarization. Threshold potential = more NA+ channels open |
What is an action potential? | cell responds, i.e. contracting |
When does the cell repolarize? | K+ channels open, diffuse out, making cell negative |
What is Na+/K+ ATPase do? | removes Na+ from cell and pumps K+ back in |
Be able to know atrophy, hypertrophy, hyperplasia, metaplasia, dysplasia | |
What four things stress damaged cells? | 1. Direct damage to proteins, membranes, DNA 2. ATP depletion 3. Free radical formation 4. Incr intracellular calcium |
What does hypoxia cause? | ATP depletion/power failure where aerobic met stops, NA/K pump slows down, cells swell w water, anaerobic met use - lactic acid produced, acid damage cell membrane, structures, DNA |
What is a free radical? | Unpaired electron in outer electron shell, unstable, reactive, removed by antioxidants, oxidative stress |
What is the difference b/n oxidation & reduction? | Oxidation: losing an electron Reduction: Gaining an electron |
What are three mechanisms of cell injury? | 1. reversible inj, cell recovery/return to normal fx 2. Apoptosis/programmed cell removal, normal process 3. Cell death/necrosis, cells swell/rupture, inflammation results |
What is Caspases? | Enzyme turned on inside cell, digest own cell proteins/DNA, then destroyed by WBC |
Apoptosis can be caused by? | 1. Signal attached to cell surface receptors 2. mitochondrial damage inside cell 3. Protein p53 activated by DNA damage |
Liquefaction, coagulation, infarction, caseous necrosis all are part of? | cell death and degradation, where cell contents released and inflammation occurs |
What is dry gangrene? | lack of arterial supply, but venous flow can carry fluid out of tissue, tissue coagulates |
What is wet gangrene? | lack of venous flow lets fluid accumulate in tissue, which liquefies and infection is likely |
What is gas gangrene? | Clostridium infection, toxins/H2S bubbles. Only type to cause crepitus. |
How do cells change with aging? | Telomeres become too short, cell can no longer divide |
Is aging caused by accumulated damage? | Have more DNA damage, more free radicals, can lose ability to repair their telomeres |