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PharmCh19
| Question | Answer |
|---|---|
| Parasympathetic = | Cholingeric -- rest and digest-- aCh |
| Sympathetic = | adrenergic -- fight or flight-- NE |
| how does the body react with the parasympathetic NS | pupils constrict, slows HR, stimulates bowls, and contracts bladder |
| What are the drugs that stimulate the parasym. NS | Cholinergic drugs |
| what are other names for cholinergic drugs | parasympathomimetics, cholinergic agonist |
| How do cholinergic drugs work | by binding to and activating cholinergic receptors and breaking down aCh |
| What are the drug effects of cholinergic drugs | increased GI stimulation, pupil constriction, increased sweating, vasodilation, decreased HR |
| Urecholine (bethanechol) is used for what | increasing tone and motility of the bladder and GI tract, it treats urinary retention, bladder atony, and post-op to get things moving --taken with meals |
| What is the drug physostigmine (antillrium) used as a reversal for | Anticholinergic poisoning and NMBAs, also in treating myasthenia gravis |
| What is the drug Aricept(donepezil) used to treat | mild to moderate alzheimers, it helps increase aCh in the brain which helps increase and maintain memory ---it is not a cure just manages symptoms |
| When should you NOT use choinergic drugs | with GI obstructions, bradycardia, hyperthyroidism, hypotension, COPD, parkinsons |
| What are the first s/s with cholinergic poisoning | SLUDGE - salivation, lacrimation, urinary incontinence, diarrhea, GI cramps, emesis |
| What is the antidote for cholinergic poisoning and cholinergic crisis | atropine - |
| What are some cholinergic crisis | shock- arrest s/s hypotension, n/v, bloody diarrhea, salivation |
| How do cholinergic blocking agents work | they block aCh- which may lead to azheimers like symptoms |
| What are other names for cholinergic blocking drugs | anticholinergics - |
| what are some effects of anticholinergic (cholinergic blocking) drugs | Dry mouth, constipation,small doses: decrease HR, decrease muscle rigidity and tremors Large doses: increase HR, cause disorientation, in general they dilate pupils, relax GI tract, cause urinary retension, decrease secretions |
| What are some uses for anticholinergic drugs | used to decrease respiratory secretions, lower BP & HR, decreases airway resistance, treats asthma, COPD, ulcers, urinary incontinence, enuresis |
| how do anticholinergic drugs affect the eyes | mydriasis - they dilate the pupils |
| What is the prototype drug, used for cholinergic OD, life support for bradycardia, and pre-op salivation reduction | atropine - |
| What anticholinergic drug is used to treat IBS | dicyclomine (bentyl) |
| What anticholinergic drug is used to treat motion sickness | Scopolamine |
| What anticholinergic drug is used to increase bladder capacity | oxybutynin (ditropan, oxytrol) |
| What anticholinergic drug is used to delay the urge to pee | vesicare |
| What is the antidote for atropine poisoning | Ahysostigmine |
| PT who take anticholinergics should be away of what fact when doing physical activities | they are at higher risk of heat stroke |
| when should you NOT use anticholinergic drugs | with glaucoma,MI, CHF, GI obstruction |
| If medication is given for myathenia gravis, when should it be given | 30 min before a meal |
Created by:
cspearsall
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