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Module 1 Meds
Generic Name | Pharm Class | Therapeutic Use/MoA | Adverse Actions | Nursing Implications |
---|---|---|---|---|
Prednisone | Glucocorticoid | Suppresses inflammatory and immune response in non-endocrine disease | Insomnia; F&E imbalance; Suppressed immune system; mood changes; Sweating; Increased appetite | Do not discontinue abruptly; Monitor weight gain, glucose levels, I&O |
Methotrexate | Cytotoxic Immune suppressant | Suppresses B&T lymphocytes. Inhibits the enzyme that breaks down folic acid, preventing synthesis of nucleic acid (DNA,RNA) | Dizziness; Seizures; Urinary retention; Renal failure; Alopecia; GI disturbances; Reduced fertility | Requires special handling; Infection; Pregnancy; Drug interactions; Monitor Labs and VS |
Diphenhydramine | Anithistamine | Decreases allergic response by blocking histamine receptors | Dizziness; In-coordination; Confusion | Over sedation; Hypersensitivity; Pregnancy; Breast feeding |
Psudoephedrine | Adrenergic Decongestant | Causes vasoconstriction of nasal mucous membranes, reducing congestion | Urinary retention; Rebound congestion; anxiety; palpitations | Cardiac disorders; HTN; Hyperthyroid; Monitor VS; Pregnancy; Breast feeding |
Furosemide | Loop diuretic | Inhibits reabsorption of Na+ & Cl- at proximal and distal tubule and in loop of Henle | Hypokalemia; Hyponatremia; Hyperglycemia; Nausea; Polyuria; Rash; Pruritus; Tinnitus; Orthostatic HTN; Circulatory collapse | Pregnancy; Breast feeding; Monitor weight, I&O, VS, Risk for ototoxicity |
Spironolactone | Potassium-sparing diuretic | Blocks aldosterone receptor sites to prevent the excretion of K+ in the distal tubule | HA; Hyperkalemia; Hyponatremia; Diarrhea; Vomiting; Rash; Pruritus | Assess diet for excessive K+ intake risk; Monitor F&E, weight, I&O; Pregnancy; Breastfeeding; |
Amoxicillin | Broad spectrum antibiotic; Anitmicrobial | Treatment of Bacterial Infection; Destroys bacterial cells by weakening cell wall | Allergic reaction; HA; Nausea, Diarrhea; Vomiting; Rash; Yeast Infection | Check allergies before administration; Monitor reaction during infusion; Check renal function |
Acetaminophen | Non-opioid analgesic; Antipyretic | Decreases prostaglandin synthesis in the CNS reducing fever and pain | Overdose; N/V, abdominal pain; hepatotoxicity | Pregnancy; Breastfeeding; Allergy; Liver disease; Alcohol use; Jaundice |
Ibuprofen | NSAID | Inhibits cyclooxygenase and has inflammatory, analgesic, and antipyretic properties. | HA; Dizziness; Nausea; Tinnitus; Dysuria; Increased bleeding time; Abdominal pain; Heartburn; Tinnitus | Pregnancy; Bleeding; Gastritis; Renal function; Caution in geriatric population; Risk for MI and Stroke |