Help
Options
Didn't know it?
click below
click below
Knew it?
click below
click below
Don't Know
Remaining cards (0)
Know
retry
shuffle
restart
0:00
Embed Code - If you would like this activity on your web page, copy the script below and paste it into your web page.
Normal Size Small Size show me how
Normal Size Small Size show me how
autoimmune disorders
autoimmune diseases and definitions
| Question | Answer |
|---|---|
| Immune System | Ability to recognize and destroy foreign cells from normal host cells. |
| Function of the lymphatic system and Spleen | Lymph nodes, spleen- RBC's are in the spleen. The spleen cleans out the RBC's. |
| Specialized Cells | Lymphocytes, Macrophages, and Antibodies. |
| Interleukins | Facilitators of communication and response in the cells. |
| Interferons | Helps with fighting off bad cells and inhibits certain tumors. |
| Cytokines | Involved in cell to cell communication, coordinating antibody and T-cell immune interactions and amplifying immune reactivity. |
| Inflammation | Occurs with injury and infection.Occurs with a vascular response or cellular response. |
| Complement | A group of proteins are made in the liver and found in the blood and interact with other cells and attach with the antigen to the foreign neighbor and engulfs them and pierces the wall and destroys the cell wall. |
| Surveillance | surveillance is done by lymphocytes that go around and kill the bad cells. |
| Hyper-responsivness | Hypersensitivity- Autoimmune diseases and Allergy. |
| Impaired Immune Response | HIV and Malignancy |
| Autoimmune Disease | Loss of self-recognition. Autoantibodies are formed against normal cells. Often the immune targets blood vessels and connective tissues. |
| Systemic Lupus Erythematosus | Is the most common and serious autoimmune disease-type 3 immune response in the capillary and causes inflammation. Inflammation causes pressure and does not allow O2 to reach the tissues and you have tissue death. |
| Pathophysiology of SLE | Hypersensitivity of B-cells, viral infection damage, autoantibodies against antigens of blood cells, immune complexes invade capillaries of organs, and stimulates inflammation that causes damage or organ failure. |
| Cutaneous Lupus | Swollen joints, swollen lymph nodes, fatigue, anorexia, fever, rash, hair loss, arthritis, arthralgia, photosensitivity, edema to legs, and pleuritic chest pain. |
| Cutaneous Lupus | Affects just the skin. |
| Manifestations of the skin in Lupus | Butterfly rash- looks like roscea on the face, lesions, alopecia, and oral ulcers. |
| Raynaud's Phenomenon | Vaso-spasms your are reducing O2 to the tissue and this happens in the arteries and arterioles. |
| Treatments for Lupus | NSAIDs, antimalarial drugs, corticosteroids, steroid-sparing drugs, and immunosupressive drugs. |
| Systemic Sclerosis (Scleroderma) | Hardening of the skin. Abnormal proliferation of fibrous connective tissue. |
| Two types of Scleroderma | Diffuse Cutaneous (systemic)- this is the worst one because you can get hardening of the lungs.Limited cutaneous- Localized to the skin. |
| Pathophysiology of Scleroderma | Overproduction of collage, the connective tissue reproduces collagen and resists pulling forces and is a little flexible. platelet aggregation and fibrosis. Disrupts normal function of internal organs; lungs, kidney, heart and GI. |
| CREST syndrome in Scleroderma | Calcinosis-deposits of clacium in the organs and tissues. Raynaud's phenomenon. Esophageal dysmotility-The thickening of the esophagus. Sclerodactyly-Thickening of the feet and hands. Telangiectasia-Redness on the face,hands, and feet. |
| Treatments for Scleroderma | NSAIDs, corticosteroids, Vasodilators, immunosuppressives, ASA, and antacids. |
Created by:
tiniekittie12
Popular Nursing sets