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Juvenile Aggres Os F
OMFP 2 Flash Card 2 - Juvenile aggressive ossifying fibroma
Question | Answer |
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Clinical features of juvenile aggressive ossifying fibroma (1) | The fibro-osseous lesion is like other types of ossifying fibroma in many aspects except they tend to have more rapid growth than central ossifying fibroma and a larger growth capacity. |
Demographics of juvenile aggressive ossifying fibroma | It is found in younger patients within their first two decade of life, with a slight male predilection. |
Microscopic features of juvenile aggressive ossifying fibroma | The specimen will appear as a central ossifying fibroma with more malignant, highly cellular and active regions (Like fibroblastic osteosarcoma). As in the other types of COF there are 2 microscopic types: trabecular and psammomatoid. |
Differential diagnosis of juvenile aggressive ossifying fibroma | Ossifying fibroma Osteoblastoma Osteosarcoma Peripheral ossifying fibroma when on gingiva Fibrous dysplasia CGCG (early lesions) |
Treatment options for juvenile aggressive ossifying fibroma | Treatment is surgical resection and in large lesions a hemi-mandibulectomy may be required to eliminate recurrence. |
Clinical features of juvenile aggressive ossifying fibroma (2) | They often will expand the cortex (maybe with perforation) These also may become large and greater than 10 cm. in diameter. |
Clinical features of juvenile aggressive ossifying fibroma (3) | Clinically these will appear as a circumscribed radiolucency or mixed radiolucency and radiopacity. |
Clinical features of juvenile aggressive ossifying fibroma (4) | A sclerotic border is present in some cases. “Ground-glass” opacification or a multilocular “honeycomb” pattern also may be observed potentially because of the rapid growth rate. |
Prognosis for juvenile aggressive ossifying fibroma | There is a high recurrence rate without aggressive surgery, so the prognosis is fair due to the recurrence potential. |
How do you diagnose juvenile aggressive ossifying fibroma? | Clinical correlation of patient history, clinical findings and radiographic interpretation will be utilized with a biopsy of the lesion for definitive diagnosis. |