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Degenerative Change
Patho
| Term | Definition |
|---|---|
| accumulated mutation theroy | the belief that evolutionary effect of adverse events declines following the age at which an organism is initially capable of reproduction. |
| antagonistic pleiotropy theory | developmental theory of aging suggesting that genes may have beneficial effects during early life, but harmful effects as the individual ages. |
| calcitonin | hormone produced by the thyroid gland that lowers the levels of calcium and phosphate in the blood and promotes the formation of bone. |
| cellular senescence | developmental theory suggesting that aging is caused by an intrinsic loss of the capicity of the cell to proliferate, triggered by a critical loss of telomere |
| chondrocalcinosis | calcification of cartilage |
| developmental theories | theory implicating the influende of genetics as the major deerminant of aging |
| dual energy X-ray absorptiometry (DEXA) | specialized, low-level radiographic technique used to measure bone density |
| error theory | the view that the ordinary user of moral language is typically making claims that involve a mistake |
| free radical theory | theory of of aging that proposes aging is caused by accumulation of damage inflicted by reactive oxygen species (ROS). |
| immune senescence | the aging of the immune system, particularly its effect on changes in lymphocyte development and function, predisposes older adults to a higher risk of latent virus reactivation. |
| immunologic theory of aging | the process of human aging is a mild and generalized form of a prolonged autoimmune phenomenon |
| kyphosis | exaggerated anterior concave curvature of the thoracic spine associated with osteporosis |
| life expectancy | the age at which 50% of a given population is expected to survive |
| lipofusion | fatty brown lipid pigment; intracellular deposition causes stiffening or rigidity of cellular structure |
| menopausal bone loss | rapid phase of bone loss in women after menopause |
| neurofibrillary tangles | twisted, helical struccture of accumulated proteins, primarily including tau; commonly associated with Alzheimer disease |
| neuroendocrine theory | developmental theory of aging suggesting that the interrelationship between neurons and associated hormones serves as the stimulus for aging |
| osteopenia | condition that occurs when the body doesn't make new bone as quickly as it reabsorbs old bone. |
| osteoporosis | condition characterized by decreased bone mass and deterioration of bone tissue; associated with increased bone fragility and susceptibility to fracture |
| sarcopenia | loss of skeletal muscle associated with aging |
| senescence | postmaturational processes that lead to diminshed homeostasis and increased vulnerability; used interchangeably with aging |
| senescent bone loss | slower loss phase that affects both men and women; associated with aging |
| senile plaque | accumulations of proteins surrounding deposits of B-amyloid protein |
| somatic mutation theory | stochastic theory of aging suggesting that the aging process is caused by impaired DNA repair, antioxidant defense, or errors in protein expression |
| stochastic theory | theory positing that aging is the result of cumulative cellular damage. |
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DocMorris
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