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hematologic drugs

pharm

QuestionAnswer
ferrous sulfate iron deficiency anemia
Vit b12 cyanocobalamin pernicious anemia
folic acid megaloblastic anemia (decreased RBC production)
factor VIII hemophilia A- clotting disorder causing increased bleeding
factor XI hemophilia B- clotting disorder causing easy bruising and bleeding
desmopressin mild hemophilia A (trauma induced, surgery)
heparin, enoxaparin prevents DVT, PE, inhibits thrombin
warfarin action prevents DVT,PE, inhibits Vit K
clopidogrel action inhibits platelet aggregation
alteplase action can break up clots
epoetin alpha action produces RBC-erythrocytes
hemophilia A and B action/instructions anaphylaxis reaction, have emergency equipment ready
desmopressin admin/A.E/instructions give 30 min before surgery, can cause hyponatremia, monitor I&O and weight
heparin action/ A.E/ interactions inhibits thrombin/hemorrhage, thrombocytopenia, DVT, don't give NSAIDs to renal insufficient pts
warfarin action/A.E/instructions inhibits Vit K, decreases blood clot but DOES NOT rid of it, hemorrhage, toxicity (IF HAPPENS GIVE VIT K), pts should use electric razor, soft toothbrush, expect 3-5 days for full effects
clopidogrel admin/A.E/interactions stop 1 week before surgery, check platelet levels, bleeding TTP, No NSAIDs or Anticoagulants
alteplase action/contraindications/interactions breaks up clot, intracranial bleeding, cardiac dysrhythmias, No previous stroke within 6 months, No surgery 2-4 weeks prior
epoetin alfa action/A.E/instructions produces RBC, DONT shake vial, hypertension, chest pain, headache, MI, DVT, monitor Hgb- different for cancer pts
protamine use for heparin overdose
when should you stop heparin platelet count under 100,000
how to monitor heparin for correct admin aPTT is 1.5-2 times clients baseline- test determines blood clotting time
heparin and oral warfarin together warfarin takes 3-5 days for full effect, then discontinue heparin
warfarin pt discharge instructions avoids NSAIDs, brush with soft toothbrush, ask before taking OTC drugs
liquid ferrous sulfate admin drink with straw, dilute with water, take with food if needed
heparin treats DVT
folic acid (IV) A.E rash
filgrastim treats chronic neutropenia (low WBC)
factor VIII contraindication aspirin
warfarin daily lab tests PT (prothrombin-protein in blood plasma that helps blood clot)/INR
alteplase instructions monitor temp, limit venipunctures, assess neurologic status, apply pressure to oozing sites
what food is high in Vit k mayonnaise
alteplase action dissolves thrombi( blood clots)
filgrastim action produces WBC-leukocytes
clopidogrel A.E thrombocytopenia (petechiae), vision changes, weakness
Oprelvekin assess for A.E ECG
aspirin action inhibits platelet aggregation by inhibiting cyclooxygenase in platelets
alteplase A.E headache
ferrous sulfate instructions eat iron enriched foods, spread dosage across each day, take on empty stomach, increase dietary fiber
warfarin pt has rectal bleeding, administer what Vit K
ferrous sulfate A.E constipation
folic acid lab test for therapeutic effect reticulocyte count- looks for amount of new RBC's
alteplase severe reaction administer what aminocaproic acid- helps blood clot
factor IX eliminates R.F what disease Creutzfeldt-Jakob's disease- memory loss with blurred vision or blindness, eventually causing dementia and even death
desmopressin A.E edema
pt taking Desmopressin what electrolyte should be monitored sodium, cause it can cause hyponatremia
factor VIII instructions have emergency equipment ready
epoetin alfa admin IV bolus over 1-3 min
epoetin alfa lab to monitor Hgb
filgrastim A.E enlarged spleen
what promotes warfarin effectiveness dietary modifications
clopidogrel contraindications PUD
administer what to ferrous sulfate toxicity deferoxamine
Created by: scoobydooamo2011
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