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PHARM-Phenothiazines

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QuestionAnswer
Indications for Phenothiazines Antiemetic or anti-psychotic
Phenothiazine identifier? -zine
Common Side Effects EPS, Photosensitivity, Neuroleptic Malignant Syndrome, Drowsiness, Sedation, Orthostatic hypotension, ACE Side Effects, Agranulocytosis
What are the signs and symptoms of NMS and Antidote? Fever over 107 degrees, Muscle rigidity, Change in LOC to stupor and coma. Antidote: bromocriptine (Parlodel) or dantrolene (Dantrium)
What are the ACE Side Effects Blurred Vision, Constipation, Urinary retention, Dry Mouth
Name Medications Chlopromazine (Thorazine); Prochlorperazine (Compazine) (antiemetic); Trifluoperazine (Stelazine); Promethazine (Phenergan) (antiemetic); Hydroxyzine (Vistaril, Atarax) ; Fluphenazine (Prolixin); Clozapine (Clozaril)
Nursing Interventions for pt. receiving phenothiazines Sunblock or avoid sunlight; Monitor for bx. changes; Monitor for NMS, ACE, and EPS; Check therapeutic levels - especially for Clozaril; Check CBC
Created by: Manik_Semiramis
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