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Drug Conversions

Basic math/conversions for blocks/epi

% concentration Grams / 100 mL
1gm = 1000 mg / 1,000,000 mcg
1mg = 0.001gm /1000 mcg
1% Lido = 1 gm / 100 mL
Converting 1 % (or 0.5, 1.5, 2%) into mg/mL (expanded) 1% = 1gm/100mL= 1000mg/100mL= 10mg/mL
Converting 1 % (or 0.5, 1.5, 2%) into mg/mL (short hand trick) Move decimal one space to the RIGHT
mg/mL to % (decimal trick) one decimal the the LEFT
1/2% = 0.5% (5mg/ml)
1/4% = 0.25% = 2.5 mg/ml
1/8% = 0.125% = 1.25mg/ml
1/16% = 0.0625% = 0.625mg/ml
1/32% = 0.03125% = 0.3125mg/ml
STOCK EPI 1:1000 1 gram in 1000 mL = 1000 mg/1000mL =1mg/ml =1000mcg/ml
Epi Conc. to mg/ml and mcg/ml 1/1000 1mg/ml 1000mcg/ml
1/10,000 Epi Conc. to mg/ml and mcg/ml .1/1 100/1
1/100,000 Epi Conc. to mg/ml and mcg/ml 0.01/1 10/1
1/200,000 Epi Conc. to mg/ml and mcg/ml 0.005/1 5/1
1/400,000 Epi Conc. to mg/ml and mcg/ml 0.0025/1 2.5/1
1/500,000 Epi Conc. to mg/ml and mcg/ml 0.0020/1 2/1
Toxic Dose with Epi/without/max single dose Lidocaine 7 5 500
Toxic Dose with Epi/without/max single dose Mepivacaine 7 5 500
Toxic Dose with Epi/without/max single dose Chloroprocaine 14 12 1000
Toxic Dose with Epi/without/max single dose Bupivacine 3 2 225
Toxic Dose with Epi/without/max single dose Levobupivacaine 3.2 2.5 N/A
Toxic Dose with Epi/without/max single dose Ropivcaine 3.5 3 N/A
Toxic Dose with Epi/without/max single dose Tetracaine 3 1-2 200
Why add epinephrine to local anesthetic Decreases blood flow to area (vasoconstriction) and blocks uptake (Should drug accidentally be administered to vascular system, decreases chances of it going to brain/other organs). Decreases the washing away of local
Lidocaine in the Brain causes seizures
Created by: lokandrews
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