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Chapter 40 Pharm
Drugs for Peptic Ulcer Disease, Pharmacology for Nurses, Adams
| Question | Answer |
|---|---|
| The digestive system consists of two basic anatomical divisions: the _____ canal and the _____ organs. | alimentary, accessory |
| The primary functions of the GI tract are to physically _____ ingested food and to provide the necessary _____ and surface area for chemical _____ and _____ of nutrients into the bloodstream. | transport, enzymes, digestion, absorption |
| The small intestine is lined with tiny projections called _____ and _____ that provides a huge surface area for the absorption of _____. | villi, microvilli, food/medications |
| Substances are propelled along the GI tract by the process of _____, rhythmic contraction of layers of _____ muscle. | peristalsis, smooth muscle |
| the _____ prevents the stomach contents from moving backwards into the esophagus, a condition known as _____. | cardiac sphincter, esophageal reflux |
| The _____ cells secrete pepsinogen and the _____ cells secrete hydrochloric acid and _____, which are essential for the absorption of vitamin B-12. | chief, parietal, intrinsic factor |
| Gastric juice is the most _____ in the body and has a pH of _____. | acidic, 1.5 to 3.5 |
| An ulcer is a/an _____ of the _____ layer of the GI tract; _____ is the most common site. | erosion, mucous, the duodenum |
| External risk factors associated with _____ (PUD) include drugs, particularly _____, _____, and _____. | peptic ulcer disease, glucocorticoids, aspirin, NSAIDs. |
| The primary cause of PUD is infection by the gram-negative bacterium _____. | helicobacter pylori. |
| GERD is defined as the _____ movement of stomach contents. | backward |
| PUD is defined as a lesion located in the _____ or ______. | stomach or small intestine. |
| Crohn's disease is defined as ulcerations in the ______. | lower small intestine. |
| Ulcerative colitis is defined as erosions in the _____. | large intestine. |
| NSAIDs are defined as _______. | nonsteroidal anti-inflammatory drugs. |
| H2-receptors are responsible are responsible for ____. | Increased acid secretion in the stomach. |
| Hypersecretion of gastric acid is a condition known as _____. | Zollinger-Ellison syndrome |
| In caring for a client with peptic ulcer disease, the healthcare provider must understand that digestive enzymes are secreted by _____, _____, and _____. | salivary glands, stomach, and pancreas. |
| The nurse is developing education materials for the client. Which of the following is not a risk factor associated with peptic ulcer disease (PUD)? (a) family history; (b) blood type AB; (c) psychological stress; (d) H. pylori. | blood type AB |
| On assessment, the nurse should recognize which characteristic symptom as most indicative of a duodenal ulcer? (a) gnawing/buring in upper abdomen; (b) nighttime pain, nausea, & vomiting; (c) bright red blood in stool; (d) bright red blood in vomitus. | (a) gnawing or burning in the upper abdomen |
| In the client with a prior history of gastric ulcers; _____, would be increased in the presence of a recurrence. | pain, briefly relieved by food |
| Inflammatory bowel disease (IBD) includes _____ and ______. | Crohn's disease and ulcerative colitis. |
| The client is overweight and complaining of an intense burning (heartburn) in the chest, which is indicative of _____. | GERD |
| In developing a plan of care for the client with peptic ulcer disease, the nurse needs to include _____, _____, and _____. | smoking cessation, abstinence from alcohol, and avoidance of caffeine. |
| Which class of drugs reduces acid secretion in the stomach by binding irreversibly to an enzyme on the parietal cells? | Proton pump inhibitors |
| Which class of peptic ulcer medications consists of alkaline combinations of aluminum hydroxide and magnesium hydroxide? | antacids. |
| Which of the following best describes the mechanism of action of sucralfate (Carafate)? | Adds a gel-like protective mucus over the ulcer |
| Why is tetracycline (Achromycin) not used in children under 12 years? | Stains forming deciduous teeth |
| Clarithromycin (Biaxin) is effective against H. pylori because: | It is effective against gram-positive and gram-negative organisms; a macrolide that can be given to people with penicillin allergies; and considered to be a broad-spectrum antibiotic. |
| Metronidazole (Flagyl) is all of the following except which one? (a) Considered an antibacterial agent; (b) Effective in the treatment of STDs; Classified as an aminoglycoside; (d) used in the treatment of protozoal infections | (c) classified as an aminoglycoside |
| A female client is prescribed nafareline (Synarel) inhalant. What administration instruction is it important for the nurse to give? | one inhalation beginning between day 2 and 4 of menstrual cycle. |
| Mr. D is receiving a HMG-CoA reductase inhibitor. He is most likely being untreated for which of the following? | High lipid levels in the blood |
| The client is to receive the following medications. Calculate: Ranitidine (Zantac) 50 mg IV in 100 mL to infuse in 30 min by microdrip. | Answer in "BOOK;" 12,000 gtts/hr |
| The client is to receive the following medications. Calculate: How many mL/hr will the nurse set the infusion pump to deliver? | 200 mL/hr |
| The client is to receive the following medications. Calculate: Aluminum Hydroxide (Amphojel) 2 T qid PO. What times would the nurse give this medication? | 1000, 1400, 1900, 2200 |
| The client is to receive the following medications. Calculate: Aluminum Hydroxide (Amphojel) 2 T qid PO. Give the correct equivalents in teaspoons, milliliters, and ounces. | 6 tsp; 30 mL; 1 ounce |
Created by:
myt1462
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