click below
click below
Normal Size Small Size show me how
Pediatrics Ch22
Medication
Question | Answer |
---|---|
Medication administration is primarily the responsibility of _____ | The nurse |
The responses of ___ differ from the responses of ___ and the responses of ___ and ___ differ from ____ | Infants – Children – Infants and children – Adults |
What is the most common OTC administered by parents | Acetaminophen/Tylenol |
What can prevent OTC medication related accidents at home | Parent education |
What is essential to providing safe pediatric medication administration | Understanding differences in Absorption, Distribution, Excretion, and Metabolism of drugs between children and adults |
What is the most important variable in predicting response to any drug therapy | Age |
What is absent from the stomach of the neonate | Hydrochloric acid |
When does the acid content of the stomach reach adult levels | Age 2 |
Medications that require an ___ ___ in the stomach for absorption may not be completely ____ if the child is under ___ | Acid medium – Absorbed – 2 |
How will a medication requiring an acid medium for absorption administered near the time of feeding be affected | Further decrease of the acid content in the stomach with further impair absorption |
Ingestion of ____ increases gastric acidity | Orange juice after age 2 |
Children under ___ have a ____ intestinal transit time than adults | 5 – Faster |
How does a child’s intestinal transit time affect medication | It may move out of the small intestines before being completely absorbed |
There may be a low amount of pancreatic enzymes under the age of ___ | 1 |
What increases the amount of absorption of topical medications | Thin stratum corneum, Larger skin surface area, Plastic diapers |
What can produce adverse reactions when applied to the buttocks and covered by a plastic diaper | Hydrocortisone and Hexacholorphene |
What slows IM drug absorption | Poor peripheral perfusion in a young infant |
What kinds of IM drugs can be administered to children under 4, and why | Water soluble to prevent precipitation |
How may a neonate’s body respond to parenteral medications | Pass through the blood brain barrier more easily |
What drugs may have a more powerful effect on neonates than adults | Those that depress respiration |
Where are most medications metabolized | Liver |
When does the liver and enzymes function at a mature level | 2 – 4 years |
Due to an immature liver, medications metabolize ____ in infants and children than in adults | |
Slower | |
What can medications given to children and infants at frequent intervals cause | Toxic levels and responses |
What can cause toxic levels of and responses to medications | Frequent intervals |
Where are penicillin and digoxin excreted | Kidneys |
What drugs are excreted in the kidneys | Penicillin and digoxin |
At what age are the kidneys able to effectively excrete medications | 1 year |
What effect does slow stomach emptying have on medication | Delays absorption |
What effect does rapid intestinal transit have on medication | Prevents the full amount from being absorbed |
What effect does unpredictable liver function have on medications | Impairs metabolism |
What effect does the kidney have on medication given to infants and children | Ineffective excretion |
What can delay absorption of medications in infants and children | Slow stomach emptying |
What can prevent the full amount of medication from being absorbed in infants and children | Rapid intestinal transit |
What can impair the metabolism of medications in infants and children | Unpredictable liver function |
What can cause ineffective excretion of medications in infants and children | Immature kidneys |
What can cause an altered response and high risk for toxicity of medications in infants and children | Slow stomach emptying, Rapid intestinal transit, Immature liver metabolism, Ineffective kidney excretion |