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Chemo Drugs

Shawnee ADNR193 Chemo Drugs

QuestionAnswer
Alkylating agents damage DNA cause break in double-strand helix
Antimetabolites interfere w/ synthesis of DNA, mimic certain essential cellular metabolites the cell incorporates into synthesis of DNA
Antitumor antibiotics modify function of DNA & interfere w/ transcription of RNA
Plant alkaloids interrupt cellular replication in mitosis at metaphase
Nitrosurea like alkylating agents & block specific enzymes
Corticosteroids disrupts cell membranes & inhibits synthesis of protein, inhibit mitosis
Hormone therapy stimulate process of cellular differentiation
Alkylating agents cell cycle-nonspecific
Antimetabolites cell cycle specific
Antitumor antibiotics cell cycle-nonspecific
Plant alkaloids cell cycle specific
Nitrosurea cell cycle-nonspecific
Corticosteroids cell cycle-nonspecific
Hormone therapy cell cycle-nonspecific
Miscellaneous destroys exogenous supply of L-asparagine (cell proliferation)
Antiestrogens suppresses mitosis at interphase
Created by: 2a2j
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