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Pharmacology Exam #3
Anti-inflammatry, fluid & electrolytes, cardiovascular
Question | Answer |
---|---|
Propranolol | Non-Selective Beta Antagonist (Block B1 and B2) |
Metoprolol | Cardio-selective Beta Antagonist (Blocks B1) |
Beta Blocker Uses | HTNAnginaDysrhythmiasMI |
Beta Blocker Adverse Effects | BradycardiaAV Heart BlockRebound Cardiac ExcitementBronchoconstrictionInhibition of glycogenolysis |
Simulation of Beta 1 | Heart: increased rate, increased contractility, increased AV conductionKindeys: renin release |
Simulation of Beta 2 | Arteriole dilation to Heart, Lungs, Skeletal MuscleBronchodilationUterine relaxationGylogenolysis (makes glucose)Skeletal muscle contraction |
Stimlation of Alpha 1 | BydriasisArteriole constriction to skin, viscera, mmVasoconstrictionMale EjaculationProstate contractionBladder trigone & sphincter contraction |
Prazasin & Doxazosin | Alpha Antagonists |
Alpha Antagonist Mechanism of Action | Blocking Alpha 1 receptors on arteriols and veins reduces peripheral resistance and venosu return (decreased preload and afterload) |
Alpha Antagonist Side Effects | Orthostatic Hypotension, Reflex tachycardia, Nasal congestion |
CarvedilolLabetalol | Alpha/Beta Blockers |
Alpha/Beta Blockers Mechanism of Action | Dilation of arteriols and veins, decreased HR and contractility, suppression of renin release |
Alpha/Beta Blockers Adverse Effects | Bradycardia, AV Heart Block, Exacerbation of Asthma, orthostatic hypotension |