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Acid-Base
pathophysiology NUR 304
Question | Answer |
---|---|
What is arterial blood gas? | A lab test that monitors the patient’s acid-base balance |
How is an ABG taken? | A blood sample from an artery; usually the radial or brachial artery |
What are the three main components of ABGs? | pH, PaCO2, and HCO3 |
Describe Acidosis | an overproduction of acid in the blood |
Describe Alkalosis | when the blood is more basic than normal |
Explain pH | the concentration of hydrogen ions and determines the acidity and alkalinity of body fluids |
What is the normal range for pH? | 7.35-7.45 |
What does a pH of < 7.35 indicate? | Acidosis |
What does a pH of 7.45 or more indicate | Alkalosis |
Explain PaCo2 | (partial pressure of carbon dioxide) shows the gas exchange between the alveoli and the external environment (alveolar ventilation) |
What is the normal range for PaCO2? | 35-45 mmHg |
What does a PaCO2 of < 35 indicate? | Alkalosis |
What does a PaCO2 of > 45 indicate? | Acidosis |
Explain HCO3 | It is a bicarbonate ion that is an alkaline substance that comprises over half of the total buffer base in the blood |
What is the normal range for HCO3? | 22-25 mEq/L |
What does an HCO3 of < 22 ndicate? | Acidosis |
What does an HCO3 of > 26 indicate? | Alkalosis |
If there are too many H+ ions in the body then the pH will be what? | Acidic |
If there are too few H+ ions in the body then the pH will be what? | Alkalosis |
Which ABG is read backward on the scale? | PaCO2 |
What are the four primary types of acid-base disturbances? | Metabolic acidosis, metabolic alkalosis, respiratory acidosis, respiratory alkalosis |
Respiratory Acidosis is caused by? | A low pH due to high CO2 levels; ineffective CO2 exchange in the lungs; associated with high K+ levels |
What will increase to compensate for acidosis? | HCO3 |
What are some possible causes of ineffective CO2 exchange in the lungs? | Asthma, pneumonia, COPD, lung carcinoma, head injury, or narcotic overdose with respiratory distress |
What are some symptoms of respiratory acidosis? | Hypoventilation (hypoxia), rapid shallow respirations, decreased BP, cyanotic skin, headaches, hyperkalemia, dysrhythmias, drowsiness, dizziness, disorientation, muscle weakness, and hyperreflexia |
Respiratory Alkalosis is caused by? | A high pH due to low CO2 |
What is done to compensate for respiratory alkalosis? | Lower HCO3 will develop to compensate |
What is respiratory alkalosis caused by? | Increased respirations, severe pain and anxiety, fever, salicylate overdose (aspirin), hyperventilation with a mechanical ventilator, thyrotoxicosis; associated with a low K+ and Ca++ |
What is metabolic acidosis? | a low pH due to low HCO3 |
How does the body compensate for acidosis? | The respiratory system will quickly respond by decreasing CO2 to compensate |
What is metabolic acidosis caused by? | An accumulation of acid or loss of HCO3 (diabetic ketoacidosis, diuretics, renal failure, excessive diarrhea); associated with increased K+ levels |
What are some symptoms of metabolic acidosis? | Headache, low BP, hyperkalemia, muscle twitching, warm/flushed skin (vasodilation), nausea, vomiting, decreased muscle tone, decreased reflexes, deep and rapier hyperventilation (Kussmaul respirations) |
What is metabolic alkalosis? | A high pH due to a high HCO3 |
What is done to compensate for metabolic alkalosis? | The respiratory system will quickly respond by increasing CO2 to compensate |
What is metabolic alkalosis caused by? | Decreased H+ or increased HCO3; excessive vomiting (HCL) or NG suctioning, excessive anti-acid intake, excessive K+ wasting diuretics |
What are some symptoms of metabolic alkalosis? | Restlessness followed by lethargy dysrhythmias (tachycardia), confusion, (decreased dLOC, dizziness, irritability), compensatory hypoventilation, hypokalemia, nausea, vomiting, diarrhea, tremors, muscle cramps, tingling of fingers and toes |
What are the first goes of ABG analysis? | To determine if it is acidosis or alkalosis |
What is the first goal of ABG analysis? | To determine if it is respiratory or metabolic |
What is the third goal of ABG analysis? | To determine if it is fully, partially, or uncompensated |
What determines if ABG is acidosis or alkalosis? | pH |
If the pH is on the same section as PaCO2 then it is classified as what? | Respiratory |
If the pH is on the same section as HCO3 then it is classified as what? | Metabolic |
What is the ABG if the pH is normal? | Fully compensated |
What is the ABG if all of the values are abnormal? | Partially compensated |
If PaCO2 or HCO3 is normal and the other is abnormal, what is the ABG classification? | Uncompensated |