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fluid & electrolytes
pathophysiology NUR 304
Question | Answer |
---|---|
What is the range for sodium? | 135-145 mEq/L |
What is the range for potassium? | 3.5-5.2 mEq/L |
What is the range for calcium? | 8.7-10 mg/dL |
What is the range for phosphorus? | 2.5-4.5 mg/dL |
What is the range for magnesium? | 1.5-2.5 mEq/L |
What is the range for chloride? | 97-107 mEq/L |
Define isotonic | Has the same tonicity as blood and does not cause fluid to shift |
Define hypotonic | Has fewer particles (more water) than blood and the fluid shifts from ECF to ICF with IV infusions |
Defer hypertonic | Has more particles (less water) than blood and the fluid shifts from ICF to ECF due to Iv infusions |
What are some examples of isotonic solutions? | normal saline and lactated ringers (LR) |
What are some examples of hypotonic solutions? | 1/2 normal saline, 0.45% NaCl |
What are some examples of hypertonic solutions? | mannitol infusion used in cerebral edema |
Define osmolality | the concentration of a solution expressed as the total number of solute particles per kilogram of solution. |
Define Osmolarity | number of osmoles per liter of solution |
What is hydrostatic pressure? | the pressure within a blood vessel that tends to push water out of the vessel |
What is osmotic pressure? | the external pressure that must be applied to stop osmosis |
What is the movement of fluid that results from an interruption between 2 opposing forces? | hydrostatic pressure and osmotic pressure |
What does increased blood volume equal to? | increased hydrostatic pressure |
What does lower albumin equal to? | reduced osmotic pressure |
What is the RAAS system? | renin-angiotensin-aldosterone system (RAAS) |
What signals the RAAS? | hypotension, hypovolemia, and low cardiac output due to low circulation |
What is the purpose of RAAS? | To increase blood pressure |
what is the first step in RAAS? | Renin is released from the kidneys and converts angiotensinogen to angiotensin 1 |
what is the second step in RAAS? | Angiotensin 1 is converted to angiotensin 2 in the lungs with the ACE converting enzyme |
what is the third step in RAAS? | Angiotensin 2 (vasoconstrictor) binds to the receptors in the adrenal cortex and activates the adrenal cortex to release aldosterone |
what is the fourth and final step in RAAS? | Aldosterone increases sodium and water reabsorption and potassium excretion by kidneys |
what is the opposite of RAAS? | natriuresis |
What is natriuresis? | excretion of a large amount of both sodium and water by the kidneys in response to excess ECF volume |
What three peptides promote natriuresis? | Atrial natriuretic peptide (ANP):atrial cells, B type natriuretic peptide (BNP):Ventricles and brain, c type natriuretic peptide (CNP):endothelial cells and ventricular cells |
What are sequestered Fluids? | fluid accumulates in body cavities normally free of fluids |
What is Hypervolemia? | fluid volume overload; blood has excessive amount of water |
What is hypovolemia? | decreased blood volume; diminished amount of water in the blood |
What are the three types of fluids? | Intracellular, extracellular, and interstitial |
Define intracellular fluid | fluid that is inside of cells |
Define extracellular fluid | fluid that is outside of cells |
Define interstitial fluid | fluid that is in between the cells and compartments "cushioning fluid" |
What is starling's law of capillary forces? | the movement of fluid that occurs at the capillary beds |
What are osmoreceptors? | located in the hypothalamus and they are stimulated by increased plasma concentration |
What is ADH? | antidiuretic hormone aka vasopressin that is synthesized by the hypothalamus and released from the posterior pituitary gland |
What is edema | swelling; excess of fluid in the ISF and ICF compartments |
What causes edema? | elevated hydrostatic pressure, decreased osmotic forces in blood, inflammation, and sodium retention due to illness or consumption of salty foods |
What is the major ion in the ECF? | sodium |
What is the major ion in the ICF? | potassium |