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125 Exam 2

QuestionAnswer
Advantage of using body box in measuring FRC FRC can be measured much faster while using the body box. FRC can be measured multiple times within 5 minutes.
How long should a smoker not smoke before a diffusion capacity test At least one hour
Purpose of adding 10% helium to a CO gas test To determine the concentration of CO in the alveoli at the beginning of the breath hold. In order to calculate DLCO CO concentration at the beginning and end of the breath hold must be determined.
Diagnostic indications for PFT To evaluate symptoms, signs, or abnormal lab tests; measure the effect of a disease on pulmonary function; screen individuals at risk of having pulmonary disease; assess preoperative risk and/or health status prior to beginning an exercise program
Monitoring indications for PFT Assess the change in lung function over time or after administration of or change in therapy; monitor for adverse reactions to drugs with known pulmonary toxicity; assess the potential effects of environmental or occupational exposures
Disability indications for PFT Assess impairment or disability from lung disease; assess risks as part of insurance evaluation
Public health indiciations for PFT Epidemiologic surveys; derivation of reference equations; clinical researc
Common source of poor PFT results An incompetent and/or unmotivated technologist
Maximum voluntary ventilation (MVV) Largest volume that a pt can move in & out of their lungs during 12secs Pts instructed to breath rapidly & deeply Low can occur in obstructive, restrictive or neuromuscular disorders Can present as a defect in vocal cord dysfunction & tracheal stenosis
Henderson-Hasselbalch equation 𝑝𝐻=π‘πΎπ‘Ž+π‘™π‘œπ‘”π»πΆπ‘‚3/𝐢𝑂2 This equation accurately describes the equilibrium relationships between pH, PCO2, and HCO3
What does PaCO2 measure? arterial CO2 content and is an indicator of the adequacy of alveolar ventilation in removing CO2 from the lungs
What does PaO2 measure? arterial O2 content and reflects oxygenation of the arterial blood
What does HCO3 measure? the arterial bicarb content and represents the metabolic component of pH regulation
P02 is measured using what kind of electrode? Clark electrode
CO2 content and alkalinity between the blood and the intracellular fluid (ICF) during exercise remain what during exercise? CO2 content may vary in the body, but the body will makeup for the difference. So the content doesn't relatively change.
Why are quality control procedures for a blood gas analyzer different from those performed in other clinical laboratory environments? Because the patient sample is fresh whole blood
Common preanalytic errors Roomair contamination Heparin dilution of sample Blood clots bc inadequate heparin Hyperventilation during collection Long delay time from collection & analysis Excessive sample metabolism Inadequate wait time between change in O2/ventilation & collection
Volatile acid elimination The lungs eliminate volatile acid as CO2 Kidneys eliminate nonvolatile acid
Organs of the body that are commonly used to regulate acid-base status Lungs and kidneys
What kind of solution is sodium bicarbonate? A buffer solution
pH is defined as the β€œnegative . . .” logarithm or exponent (to the base of 10) of the [H+]
Data needed for a PFT Height, age, sex, and race or ethnicity
Normal pH 7.35-7.45
Normal PaCO2 35-45
Normal HCO3 22-26
Normal PaO2 80-100
What does it mean when the baseline of an MVV test is gradually rising? There is airtrapping present
Calibration test for spirometry: Should be done once daily, uses a 3mL syringe
What is measured and more importantly, what is calculated with a PFT Measured: FVC, FEV1 Calculated: TLC. RV
How many times can a PFT test be repeated 8 times
What is the best indicator for obstructive lung disease? Decreased flows (FEV1 and FEV1/FRC)
Pre and post bronchodilators tests 12% is the magic number. FEV1 must change by 200 mL or 12%
Tidal volume (Vt): the volume of gas inhaled or exhaled during quiet breathing
Inspiratory reserve volume (IRV) the maximum volume of gas that can be inspired from the end of a normal inspiration
Expiratory reserve volume (ERV) the maximum volume of gas that can be expired from the end of a resting expiration
Residual volume (RV) the volume of gas remaining in the lungs after a maximal expiration. By definition, this volume cannot be exhaled
Vital capacity (VC): the maximum volume of gas that can be exhaled from the lungs after a maximal inspiration or inhaled from a point of maximal exhalation
Inspiratory capacity (IC) the maximum volume of gas that can be inspired from the normal end-expiratory position
Functional residual capacity (FRC) the volume of gas remaining in the lungs at the end of a resting expiration
Total lung capacity (TLC) the volume of gas in the lungs at the end of a maximal inspiration
When percent of predicted FVC is low an obstructive disease is indicated
When percent of predicted FEV1 is low a restrictive disease is indicated
When both are low considered combined restrictive and obstructive
> or = 80% normal
70 – 79% mild
60 – 69% moderate
50 – 59% moderate to severe
< 50% severe
<35% VERY severe
Created by: K.Moskowitz
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