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inflammation

QuestionAnswer
goals of inflammation 1. keep the injury contained 2. prevent the spread 3. bring the body's defenses to the region under attack
acute inflammation examples sunburn, basic bug bite, sprained ankle
3 phases of acute inflammation 1. inc. vascular perm: histamine & bradykinin dilate vessels; wbcs can go to the site on injury 2. cellular chemotoxins: chemical signals attract wbcs +platelets; margination 3. systemic response- how the body responds to the inflammatory mediators.
What is margination? when the wbcs line up along the endothelium and release the inflammatory mediators
What is leukocytosis? elevated number of WBC (>10,000)
What is a leukemoid reaction? severe elevation in number of WBC (>50,000)
5 classic signs of inflammation 1. Redness (rubor) 2. Swelling (tumor) 3. Heat (calor) 4. Pain (dolor) 5. loss of function
what does a shift to the left mean in regard to WBCs? increased neutrophil production in the bone marrow
purulent exudate pus like
transudate exudate watery fluid (like that causing a pleural effusion)
what substance causes fever pyrogens activate prostaglandins to reset the hypothalamic temperature to a higher temp.
Created by: hcollie2
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