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Stack #38942

RRC Maintenance - HIV/AIDS

questionanswer
order of infection of cell by HIV virus viral attachment -> viral penetration/fusion -> uncoating -> reverse transcriptase -> integration -> viral latency and protein synthesis -> cleavage and viral assembly -> budding...starts all over again
s+sx of acute retroviral syndrome can be asymptomatic to flu-like symptoms 2-6 weeks post infection
s+sx of chronic HIV infection may be asymptomatic, but may also have enlarged lymph nodes, lack of energy, weight loss, frequent fever and night sweats, persistent or frequent yeast infections, persistent skin rashes/flaky skin, short-term memory loss, frequent severe herpes infection
AIDS infection CD4 <200 and opportunistic infection
s+sx of AIDS infection coughing/SOB, seizures/lack of coordination, confusion/forgetfulness, severe persistent diarrhea, fever, weight loss, N+V, abdominal cramping, weight loss and extreme fatigue, severe headache, coma
if western blot postive HIV positive status
risk factors aboriginal people in Canada, injection drug users, MSM, sexual transmission (vaginal, anal, oral), infected blood, accidental needle stick, mother to child transmission in pregnancy or through breastmilk
virulogic failure HIV still detectable in blood 48 weeks after starting treatment or is detected again after viral load was undetectable
immunologic failure CD4 decreases further or does not increase within 1st year of therapy
clinical failure opportunistic infection or decline in health after at least 3 months on ARV therapy
nucleoside reverse transcriptase inhibitor contains faulty imitation of T-cells nucleotides which prevents formation of the double strand DNA
non-nucleoside reverse transcriptase inhibitor attach to the reverse transcriptase enzyme preventing it from functioning
protease inhibitors binds to protease enzyme and prevents separation of substances
ABCD of HIV Abstinence, Be faithful, Condom, Disclosure of HIV status
average person living with HIV a "she" with 3-4 children lives in africa and has a poor life expectancy
Created by: bella83
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