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Stack #39439/Antibio
Antibiotics
Question | Answer |
---|---|
S &S of infection | Pain, erythema, loss of function, swelling, heat, fever, drainage |
What is selective toxicity? | the ability of a drug to injure a target cel/organism w/o injuring other cells/organisms that are in intimate contactwith target; this is how antibiotics work |
What is the difference between bacterialcidal & bacteriostatic? | Bacteriocidal-kills bacteria; bacteriostatic- stops bacterial reproduction w/o killing bacteria and requires an immune response |
What is an suprainfection? Why? What is the most common | New infection that appears during course of Tx for primary infection. related to decrease in normal flora. Usually yeast infection |
What are the two classifications of Antimicrobial Drugs | Narrow & broad spectrum |
When should cultures be obtained? | before initiation of antibiotic therapy |
What are factors leading to resitance of antibiotic Tx? | overuse/indiscriminant use; use in livestock; preventative; used to tx viral infections |
What must happen to an individual for them to be allergic to an antibiotic | must have had a previous exposure (aware or unaware) |
What are 2 types of resitance to antibiotic therapyand describe each? | inherent-bacteria resistant to certain drug; acquired- genetic change that converts previously drug-sensitive bacteria to a resistant one |
S & S of suprainfection? | diarrhea, black furry tongue, vaginal/anal itching, candida |
When can an allergy to antibiotics occur? | At any time of tx and up to 2 wks after therapy |
If a pt is allergic to penicillin, what else may they be allergic to ? What is this called? | other cephlasporins and sulfa; called cross-sensitivity. |
S & S of anaphylaxis of antibiotic | nausea, vomiting, pruritus, laryngeal edema, tachycardia, dyspnea, diaphoresis, loss of consciousness |
How do we tx an anaphylaxis reaction to antibiotics? | Maintain airway w/ O2, use epinephrine, steroids, administer CPR if needed and obtain IV access |
What should be included in educating patients about antibiotics? | take as prescribed, take full courser therapy, manage missed doses, avoid sharing,S & S of allergic response, some antibiotics may reduce effectiveness of oral contraception |
When administering penicillin, what must the nurse take into consideration in regards to the 5 rights of medication administration | The route; some penicillin can be given in a certain route |
Narrow spectrum penicillin are the first choice of antibiotics for what type of bacteria? | Gram positive cocci |
What route can Penicillin V/VK be given? | PO; no IV,IM |
What is the most frequently prescribed antibiotic and for what? | Amoxicillin for ear infections |
What may a patient want to avoid when taking a cephalosporin? Why? | Alcohol; produces GI distress, hypotension, tachycardia, SOB |
What is an increased risk when giving IV cephalosporins? | Phelebitis |
If a patient is on Vancomycin what might the nurse want to watch for ? What will you do if this occurs? | Red Man syndrome-slow rate; Watch patency of vein in IV-change if needed; Decrease in BP is first sign of ototoxicity; monitor labs for peak and trough |
What are the AR for Vancomycin | nephrotoxicity, ototoxicity, permanent hearing loss, leukopenia, red man syndrome |
What type of infections are treated w/ Vanco | Staph, psuedomembranous colitis, MRSA |
Tetracyclines are the #1 choice used to tx....?What else does it tx | acne; PUD, RA, chlamydia, cholera |
What are the AR of tetracyclines? | Photosensitivity, decrease Ca++ effects bones & teeth, suprainfection, GI irritation |
Gentamicin is used to tx ....? | E. Coli infections |
What are the A/R of Gentamicin | ototoxicity, nephrotoxicity, gi distress |
What is a CI for using Ciprofloxacin? | Children under 18-- may cause tendon rupture esp. in Achilles tendon |