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P&P 2010 infl k
P&P 2010 inflmation k
Question | Answer |
---|---|
Anything that causes tissue/cell damage, Injury (Direct damage),Chemicals,Physical agents – heat, cold,Foreign bodies, Ischemia, Infection are causes of ? | inflammation |
One component of the second line of defense.is | inflammation |
Neutralize the cause,Keep damage localized,Establish an environment suitable for repair and healing are objectives of ? | inflammation |
A sequential response is called | inflammation |
Suffix – itis is an | inflammation |
a cellular bag of granules located in loose connective tissues close to b.v.’s is a | Mast cell degranulation |
Basophils in blood serve the ? | same function |
the release of histamine is called | Degranulation |
what stimulates the release of chemical mediators & cytokines | |
Kinins, Complement, Prostaglandins are | chemical mediators |
what causes Vasodilation, increased vascular permeability, bronchoconstriction, vomiting, stimulates nerve ending for pain & itch | histamine |
what is Stored in body fluids (inactive),Activated by histamine & dying WBC’s, | Kininse eg Bradykinin |
increased & prolong vasodilation, and increased vascular permeability are started by | histamine kept going by kininse |
total of ? Complments | 20 |
Complement Cascade is Synthesized by the | liver |
Tissue injury, and Antigen-antibody reaction initiates | cascade of complements |
complements that change surface tension of foreign cells so phagocytes can adhere (C3b) are called | Opsonization |
Chemical mediators found in all body tissues that act locally where they are released are called | Prostaglandins |
Vasodilation,increase vascular permeability, Control platelet function, increase sensitivity to pain are actions of | inflammation |
? are Chemical messengers, and Proteins secreted by cells | Cytokines |
Monokines stimulate monocytes,Lymphokines stimulate lymphocytes- Immune response in ? | inflammation |
Redness, Swelling, Heat, Pain, Possible Loss of Function are sings of ? | inflammation |
WBC’s are attracted to the site by bacteria, tissue debris & cytokines during ? | Chemotaxis |
when WBC’s “line-up” (Pavementing)its called | Margination |
when WBC are ‘Squeezing through’ to the tissues its called | Diapedesis |
1st to arrive at the site of injury are the (within 90 minutes) | neutrophils |
2nd –to arrive at sight of in injury | monocytes |
macrophages are what type of leukocyte | big eaters |
also release ? which causes a fever | Interleukin 1 |
Fever, Leukocytosis, are signs of ? | systemic inflammation |
? digests dead cells | macrophages |
? eats the forgein cells | phagocytes |
monocytes make ? | macrophages |