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Stack #39638/adrenal
adrenal cortcoids
Question | Answer |
---|---|
What does excess Glucocorticoids cause? How is this characterized? | Cushing's syndrome;obesity, hyperglycemia, glycosuria, HTN, appearance of potbelly, moon face, and buffalo hump |
What does adrenal insufficiency cause? How is this characterized? | Addison's dz; weakness, emaciation, hypoglycemia, increased pigmentation of skin and mucous membranes |
What must patients be advised of when taking glucocorticoids about dosage and supply? | Take 2/3 in am & 1/3 in pm;At times of stress dosage must be increased, have ER supply w/ at all times including injectable plus oral med, wear ID bracelet for ER |
What are S & S of adrenal crisis? What can this be caused by? | hypotension,weakness, dehydration, vomiting diarrhea; adrenal failure from abrupt withdrawal of glucocorticoid therapy |
What is the tx of adrenal crisis? | Rapid replacement of fluids, salt, glucocorticoids, and sugar; injecting 100mg of hydrocortisone IV bolus followed by IV infusion of NS w/ dextrose, addtl hydrocortisone given 100mg/8hr |
What are AE of glucocorticoids? | Adrenal insufficiency, infection, PUD, muscle weakness, cushing appearance |
What are the uses for glucocorticoids? | suppress inflammation, immune response, replacement therapy for adrenal insufficiency |