Help
Options
Didn't know it?
click below
click below
Knew it?
click below
click below
Don't Know
Remaining cards (0)
Know
retry
shuffle
restart
0:00
Embed Code - If you would like this activity on your web page, copy the script below and paste it into your web page.
Normal Size Small Size show me how
Normal Size Small Size show me how
P&P 2010 immunity k
P&P 2010 immunity k
| Question | Answer |
|---|---|
| To destroy foreign agents, Prevent development & growth of abnormal cells, is the function of what ? | Immune System Function: |
| Key Blood Cell Involved is immunity is the | Lymphocyte |
| another word for Foreign, “Non-self” is | antigen |
| viruses, bacteria, fungi, parasites what type of antigen | Infectious agents |
| pollens, foods, bee/snake venom are what type of antigen | Environmental |
| drugs, vaccines, transfusions, transplanted tissue are what type pf antigen | Medical – |
| antigens get the immune system to generate | antibodies |
| A marker (on 6th chromosome) that marks all cells belonging to that person and prevents immune system from attacking itself is called | Major Histocompatability Complex MHC |
| First Line – Surface Membrane Barriers, Intact skin, Intact Mucous Membranes, Mucus, Nasal hair,Cilia,Gastric juice,Lacrimal secretions (tears),and Saliva are what line of defence | first line of defense |
| Nonspecific – Phagocytosis, Neutrophils & Monocytes → Macrophages, Inflammatory response,Fever and Antimicrobial Proteinsis what line of defense | second line of defense |
| -what prevents viral reproduction in surrounding cells | Interferon |
| what type of cell injects ‘perforin’ to kill virus / cancer cells | natural killer cells (NK) |
| Cell - attacked by virus - secretes small protein …? | interferon (INF) |
| ? cannot save that cell - diffuses into nearby cells & prevents viral replication | interferon |
| Not specific thus, interferon (INF) protects against | any virus |
| what also activates macrophages & NK cells in the anticancer role | |
| Nonspecific lymphocytes are also called | natural killer cells |
| what attacks membranes & ‘shoot it’ with chemicals (perforins) → kills nucleus | interferon |
| what can attack viruses & cancer cells | interferon |
| a Specific Defenses - Immune Response- Specific,Systemic it has memory – stronger attack with each encounter (secondary response), and LYMPHOCYTES is what line of defense | third line of defense |
| what does R.A.AT stand for | recogination, activation, attack |
| Different lymphocytes have receptors for different antigens, When a lymphocyte finds its “match”, it binds it to its receptor is what step in the immune response | recognition first |
| The binding stimulates the lymphocyte to start cell division ➵ clonal expansion (1 → 2 → 4 → 8 etc) is what step in the immune response | activation second |
| Attack is started against all antigens of the type that were ‘recognized’ is what step of the immune response | attack third |
| B cells –are what type of immunity | |
| Originate in bone marrow, Travel to Thymus gland to mature, Once mature – divide the ‘workload’ is what type ofimmunity | Cell-Mediated ImmunityT Cells |
| what type of cell directly attacks virus' with ‘perforins’ | Cytotoxic T-cells |
| what type of cell Releases lymphokines to - Activate more T-cells, Stimulate macrophages, Attract neutrophils, Signal B-cells to start producing antibodies | Helper T-cells |
| what inhibits T & B cells | Suppressor T-cells |
| what type of cell Remembers this antigen for future reference | Memory T-cells |
| B cells - bone marrow, Migrate to lymph nodes is what type of immunity | Humoral Immunity (B Cells) |
| Clonal Expansion of B cells is the ? | Primary Response |
| when antibodies attack antigens its called | Neutralization |
| what binds antigens together ? | Agglutination |
| what allows phagocytosis ? | Opsonization |
| what activates the complement cascade? | lysis |
| what triggers mast cell degranulation | inflammatory response |
| what contains microbes that have been killed or attenuated | vaccine |
| what contains bacterial toxins that have been modified to destroy toxicity | toxoid |
| Both vaccine and toxoid induce antibody formation without causing severe disease therefore it creaits what type of immunity? | active immunity |
| Routine immunization of children, Adults against tetanus, Immunization for a specific disease for high risk groups, Prior to travel to area where a disease is prevalent are ? | indacations of use for a vaccine |
| what measures the level of antibodies in the blood | titre Contraindications |
| During febrile illnesses, Immunosuppressive drug therapy, Immunodeficiency states – eg. Leukemia, and Pregnancy what is contraindicated | vaccines |
| what type of vaccine is formulated annually,Grown in chick embryos – allergy to eggs, Single 0.5 ml IM dose | influenza vaccine |
| what are made from an antigen/organism, Injected, and the B cells in the blood respond producing antibodies. | vaccines |
| what binds to the antigen to "neutralize“ or inactivate it | |
| what are produced and remain ready to respond against subsequent infection with the same disease causing agent | memory cells |
| Provide temporary passive immunity for people already exposed to or experiencing a disease | Immune Serums and Antitoxins |
| what is the goal of Immune Serums and Antitoxins | prevent or modify disease |
| what aids in diagnosing tuberculosis | Tuberculin |
| T cells are what type of immunity | cell mediated immunity |
Created by:
kfroel4
Popular Nursing sets