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Term

non opioid analgesic
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NSAIDs
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TermDefinition
non opioid analgesic mild to moderate pain; 1 - 5; NSAIDs, acetaminophen
NSAIDs aspirin, ibuprofen, naproxen; analgesia, anti inflammatory, anti platelet, antipyretic; something with swelling
acetaminophen analgesia, antipyretic; no anti inflammatory; fever and headache
opioid analgesic moderate to severe pain; 6 - 10; morphine, fentanyl, oxycodone
migraine headache unilateral, throbbing pain, nausea vomiting, photophobia
migraine patho neurovascular events in cerebral cortex
cluster headache severe unilateral non throbbing pain, located around eye
selective serotonin 1 receptor antagonists for headaches; sumatriptan vasoconstriction of cranial arteries; suicidal ideation and cardiac arrest
acetaminophen therapeutic range max 4g day, max if daily 2g
acetaminophen toxic effects hepatotoxicity and renal failure; antidote is acetylcystine
aspirin therapeutic level 15 to 30 mg
aspirin antidote sodium bicarbonate; enhances elimination in the urine, given until urine pH is between 7.5 and 8
morphine risk respiratory depression; antidote is naloxene
aspirin interventions do not take with alcohol or warfarin, discontinue 7 days before surgery, can cause GI distress
aspirin side effects tinnitus, dizziness, GI bleeding and ulceration, reye's syndrome
visual pain scale choose a number 0 to 10 that best describes pain
FLACC face, legs, activity, cry, consolability
OUCH scale wong baker faces (think emojis)
non verbal pain scale for cognitively impaired, emotion, movement, verbal cues, positioning and guarding
transdermal patch opioids around the clock pain control, reduces ups and downs of pain
erythema redness, blood accumulates in areas of tissue because of release of chemical mediators
edema swelling, plasma leaks into interstitial tissues
heat blood accumulation and result from pyrogens (produce fever)
pain tissue swelling and release of chemical mediators
loss of function accumulation of fluid at the tissue injury site
NSAID decrease inflammation, relieve pain, reduce elevated body temperature, inhibit platelet aggregation
first generation NSAID salicylates - aspirin; inhibits platelet aggregation
second generation NSAID selective COX - 2 inhibitors - celecoxib, leaves the protection of the stomach lining intact so no gastric bleeding occurs
use of second generation NSAID osteoarthritis, rheumatoid arthritis, dysmenorrhea, ankylosing spondylitis
black box for second generation NSAID increase risk for CV events, increase risk for serious GI events in history with peptic ulcer disease
DMARDS alleviate symptoms of RA, psoriatic arthritis, severe psoriasis , crohn disease, ulcerative colitis
infliximab administered IV, DMARD, side effects (flu like), abdominal pain, weight loss, rash, alopecia, dry skin
infliximab adverse effects chest pain, seizures, bone fractures, increased hepatic enzymes, anemia, neutropenia, pancytopenia, SJS
DMARD side effects neutropenia, monitor vital signs for infection, CBC for WBC
corticosteroid use autoimmune disorder or flare up, COPD
corticosteroid teaching taper dose when discontinuing; longer term use has side effects like increased appetite, tachycardia, edema, sodium and water retention
colchicine alleviates gout symptoms but does not decrease inflammation, does not inhibit uric acid synthesis and does not promote uric acid excretion
colchicine teaching take with food to avoid GI distress
allopurinol uric acid inhibitor, prevents gout attacks; first choice
allopurinol side effects dry mouth, arthralgia, pruritus, erectile dysfunction, bradyacrdia, hyperglycemia, blood dycrasias, SJS
allopurinol interventions record urine output, monitor renal and hepatic function, increase fluid intake, yearly eye exams
probenecid blocks reabsorption of uric acid and promotes excretion, can be taken with colchicine
probenecid side effects kidney stones, flushed skin, sore gums, severe blood dyscrasias - sulfinpyrazone
Created by: ahommel
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