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Term | Definition |
---|---|
non opioid analgesic | mild to moderate pain; 1 - 5; NSAIDs, acetaminophen |
NSAIDs | aspirin, ibuprofen, naproxen; analgesia, anti inflammatory, anti platelet, antipyretic; something with swelling |
acetaminophen | analgesia, antipyretic; no anti inflammatory; fever and headache |
opioid analgesic | moderate to severe pain; 6 - 10; morphine, fentanyl, oxycodone |
migraine headache | unilateral, throbbing pain, nausea vomiting, photophobia |
migraine patho | neurovascular events in cerebral cortex |
cluster headache | severe unilateral non throbbing pain, located around eye |
selective serotonin 1 receptor antagonists for headaches; sumatriptan | vasoconstriction of cranial arteries; suicidal ideation and cardiac arrest |
acetaminophen therapeutic range | max 4g day, max if daily 2g |
acetaminophen toxic effects | hepatotoxicity and renal failure; antidote is acetylcystine |
aspirin therapeutic level | 15 to 30 mg |
aspirin antidote | sodium bicarbonate; enhances elimination in the urine, given until urine pH is between 7.5 and 8 |
morphine risk | respiratory depression; antidote is naloxene |
aspirin interventions | do not take with alcohol or warfarin, discontinue 7 days before surgery, can cause GI distress |
aspirin side effects | tinnitus, dizziness, GI bleeding and ulceration, reye's syndrome |
visual pain scale | choose a number 0 to 10 that best describes pain |
FLACC | face, legs, activity, cry, consolability |
OUCH scale | wong baker faces (think emojis) |
non verbal pain scale | for cognitively impaired, emotion, movement, verbal cues, positioning and guarding |
transdermal patch opioids | around the clock pain control, reduces ups and downs of pain |
erythema | redness, blood accumulates in areas of tissue because of release of chemical mediators |
edema | swelling, plasma leaks into interstitial tissues |
heat | blood accumulation and result from pyrogens (produce fever) |
pain | tissue swelling and release of chemical mediators |
loss of function | accumulation of fluid at the tissue injury site |
NSAID | decrease inflammation, relieve pain, reduce elevated body temperature, inhibit platelet aggregation |
first generation NSAID | salicylates - aspirin; inhibits platelet aggregation |
second generation NSAID | selective COX - 2 inhibitors - celecoxib, leaves the protection of the stomach lining intact so no gastric bleeding occurs |
use of second generation NSAID | osteoarthritis, rheumatoid arthritis, dysmenorrhea, ankylosing spondylitis |
black box for second generation NSAID | increase risk for CV events, increase risk for serious GI events in history with peptic ulcer disease |
DMARDS | alleviate symptoms of RA, psoriatic arthritis, severe psoriasis , crohn disease, ulcerative colitis |
infliximab | administered IV, DMARD, side effects (flu like), abdominal pain, weight loss, rash, alopecia, dry skin |
infliximab adverse effects | chest pain, seizures, bone fractures, increased hepatic enzymes, anemia, neutropenia, pancytopenia, SJS |
DMARD side effects | neutropenia, monitor vital signs for infection, CBC for WBC |
corticosteroid use | autoimmune disorder or flare up, COPD |
corticosteroid teaching | taper dose when discontinuing; longer term use has side effects like increased appetite, tachycardia, edema, sodium and water retention |
colchicine | alleviates gout symptoms but does not decrease inflammation, does not inhibit uric acid synthesis and does not promote uric acid excretion |
colchicine teaching | take with food to avoid GI distress |
allopurinol | uric acid inhibitor, prevents gout attacks; first choice |
allopurinol side effects | dry mouth, arthralgia, pruritus, erectile dysfunction, bradyacrdia, hyperglycemia, blood dycrasias, SJS |
allopurinol interventions | record urine output, monitor renal and hepatic function, increase fluid intake, yearly eye exams |
probenecid | blocks reabsorption of uric acid and promotes excretion, can be taken with colchicine |
probenecid side effects | kidney stones, flushed skin, sore gums, severe blood dyscrasias - sulfinpyrazone |