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non- receptor mech.
pharmacology FRMB2612
receptor mechanism | example |
---|---|
Drugs block ion channels | local anaesthetics, calcium channel blockers treatment for hypertension |
Drugs enhance ion movement (neurotransmission) | antidepressants |
Drugs inhibit enzymes | MAO - treatment for depression; COX - treatment for inflammation; ACE – treatment for hypertension; Carbonic anhydrase treatment for glaucoma |
Drugs act by chemical reactions | antacids neutralise gastric acid |
Drugs cause cytotoxic actions | anti-cancer drugs |
Drugs inhibit DNA/RNA synthesis | antibiotics, anticancer drugs, antivirals |
Drugs kill bacteria, fungi | antibiotics, anti-fungal drugs |
Drugs act by physical properties | fiber laxatives |
Drugs inhibit pumps in cell membrane | Na/K ATPase - treatment for heart failure; Proton pump – treatment for peptic ulcer |
Drugs have Metal chelating agents | desferrioxamine binds to iron |