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Pharm F Endocrine
Question | Answer |
---|---|
Hypoglycemia | Weak, dizzy, anxious N/V Cold, clammy, diaphoretic Headache, confusion |
Hyperglycemia | Polyuria Polydipsia Polyphagia |
Glipizide education | For hyperglycemia Avoid if allergic to sulfa Avoid alcohol Increases insulin secretions 30 mins before breakfast, skip if unable to eat |
Glipizide ADRs | Hypoglycemia Weight gain N/V/D Hepatotoxicity |
Acarbose education | For hyperglycemia Inhibits breakdown of complex carbs Does not cause hypoglycemia 3x a day w/ first bite of food Hypoglycemic? Use milk, juice, glucose tablets |
Acarbose ADRs | GI distress Hypoglycemia w/ insulin or sulfonylurea |
Lispro | Rapid Clear Peak: 30mins - 3 hrs Give just before or w/ food |
Regular | Short acting Clear Peak: 2 - 5hrs IV |
NPH | Regular acting Cloudy Peak: 6 - 14hrs Eat food at start of peak If given at nighttime, eat bedtime snack |
Glargine (Lantus) | Long acting Peak: none DO NOT MIX with other insulins Used in combo with regular For 6 years and older |
Mixed Insulins | Combine rapid and intermediate Fewer injections |
Levothyroxine education | For hypothyroidism Lifelong Contain lactose Admin in morning on empty stomach Safe for pregnancy Contraindicated in MI, HTN, angina, diabetes PO or IV |
Levothyroxine ADRs | Overmedication = hyperthyroidism (hold if suspected) |
Methimazole education | For hyperthyroidism Once daily 3 to 12 weeks for effect Does not destroy existing thyroid hormone |
Methimazole ADRs | Agranulocytosis (low WBC count) Contraindicated in 1st trimester of pregnancy |