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Pharm F GI
Question | Answer |
---|---|
Omeprazole education | For healing ulcers Proton-pump inhibitor May increase blood levels of Benzos, phenytoin and warfarin Needed in people with NG tubes etc. 30 mins before meals, swallow tabs whole Consult HCP if OTC use exceeds 2 weeks |
Omeprazole ADRs | Diarrhea, abd pain, nausea, headache Long term use (pneumonia, osteoporosis, C. Diff, hip fx, hypomagnesmia) |
Sucralfate education | Protects from acids, pepsin, bile salts Used for duodenal ulcer, NSAID related ulcer Take 1-2 hours before antacid, other meds Safe in pregnancy |
Sucralfate ADRs | Constipation |
Misoprostol education | Inhibits acid secretion Increases bicarbonate, mucus production Used to prevent NSAID related ulcers Take with meals No safe for pregnancy |
Misoprostol ADRs | N/V/D Flatulence, abdominal pain |
Doscutate education | Laxative/softeners Preventative! Draws water into stool Capsules made of pigskin. |
Loperamide education | For (nonspecific diarrhea, inflammatory bowel, antibiotic related diarrhea, excess ileostomy discharge) Chemically related to opioids (given with atropine) Do not self treat NOT FOR salmonella, shigella related diarrhea |
Loperamide ADRs | Syncope, hypotension and death Risk for heart issues at high doses |
Metoclopramide education | Stimulates GI motility Used for (GERD, diabetic gastroparesis, prevents emetogenic chemotherapy and N/V) Improves lactation |
Metoclopramide ADRs | Restlessness Drowsy, fatigue EPS (tremors, akathisia, chorea [twitching], dystonia [rhythmic jerks], athetosis [writhing movement]) |
Ondansetron education | Antiemetic, PO or IV Serotonin receptor antagonist Do not remove tablet from pack until administration |
Ondansetron ADRs | Diarrhea, headache, prolongation of QT |
Prochlorperazine education | Antiemetic, IM or IV Commonly used to treat post operative nausea and vomiting (PONV) |
Prochlorperazine ADRs | Dry mouth, blurred vision, urinary retention EPS |