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action mechanism of pennicillin
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MICRO ANTIMICROBIAL
action, use, mechanism, of antomicrobials
| Question | Answer |
|---|---|
| action mechanism of pennicillin | Beta Lactam disruption of peptidoglycan |
| antibiotic | substance produced by an organism that is toxic to bacteria |
| antimicrobial | chemical compound toxic to microbes. |
| Chemotherapy | |
| prophylaxis | |
| Erythromycin uses | Streptococcal infections, syphilis,respiratory infections, mycoplasmal infections, Lyme disease; |
| AZT | Antiviral, a NARTI, Blocks DNA replication of Virus |
| Beta-lactamase | Enzyme evolved by bacteria to protect against beta lactam antibiotics |
| In vitro | in a test tube or lab apparatus |
| Eye | |
| Actinomycetes | Actinomycetales are Gram positive |
| Penicillin | Antibiotic segment/class that attacks cell wall (beta lactam) of bacteria. First discovered by Fleming |
| Cephalosporin | Antibiotic segment/class that attacks cell wall (beta lactam) of bacteria. From cephalosporin mold |
| Aminoglycosides | antibiotic class/segment that blocks protien synthesis by blocking 30s site on ribosome; ototoxic |
| Chloramphenicol | blocks peptide formation |
| Antibacterial drugs which target protien synthesis (2 ) | Streptomycin, Gentamycin/wpnmf//// |
| Classes of drugs which attack cell wall (3 ) | Penicillin, cephalosporins, Vancomycin/wall//// |
| Classes of drugs which block protien synthesis @ Ribosome | Aminoglycosides, Tetracyclines, Ketalods, Chloramphenicol, "mycins", lincosamides/protien//// |
| Antibacterial drugs which attack cell wall (3 ) | Bacitracin, Isoniazod, Vancomycin/wall/bacteriacide/// |
| Classes of drugs which block folic acid | Sulfonamides, Sulfones, trimethaprim/folic acid//// |
| Classes of drugs which block DNA/RNA replication | Flouroquinalones, rifampin/nucleics/bacteriacide/// |
| Classes of drugs which block cell membrane | polymixins,/membrane//// |
| Major drug for tuberculosis | Isoniazid/wall/bacteriacide/// |
| major drug for fungal infection (widespread) | Amphitericin B/membrane/fungicide/// |
| magor drug for GI tract infections | ///// |
| Antivirals, modes of action (3) | (1) penetration prevention, (2)translation/transcriptoin block, (3)maturation block///// |
| antimalarial drug | chloroquin, ///// |
| respiratory tract infections- Resistant Strep Pneumonia | Ketek///// |
| Candidas yeast/fungal infections | nystatin///// |
| Acne | Clindomycin/protien/bacteriacide/// |
| BBB crossers | Cephalosporins, Gen 4/wall/bacteriacide/broad/High toxicity/ |
| mitochondrial toxicity | NARTI DRUGS, AZT, Retroviron///// |
| NARTI | Nucleotide Analog reverse trnscriptiion inhibitors///// |
| Tetracycline Antibiotics, gram uses | Gram -. Gram + rods and cocci, /protien/bacteriacide/broad/Low toxixity/ |
| Tetracycline Antibiotics, uses diseases, (3) | Rocky mountain S.F. Lymes, Mycoplasma Pnuemonia/protien/bacteriacide/broad// |
| Chloramphenicol | Extremely toxic, /protien/bacteriacide/broad/High toxicity/ |
| Erythromycin, used to treat: (4) | Mycoplasma Pneum. ; legionellis, Chlamydia, pertussis/protien/bacteriacide/broad/Low toxixity/ |
| Clindomycin | broad spec/ GI sensitivity/protien/bacteriacide/broad/Low toxixity/ |
| Streptomycin | Aminoglycoside, used on B. Plague, tularemia, Tuberculosis/protien/bacteriacide/broad/High toxicity/neuro, ototoxic |
| Gentamycin | Aminoglycoside, used on Gram neg. rods/protien/bacteriacide/broad/Low toxixity/ |
| Rifampin | Myobacterial infections, TB, Leprosy/nucleics/bacteriacide/narrow// |
| Grisofulvins | Athletes foot , nephrotoxic/membrane/fungicide/narrow/High toxicity/nephro |
| polymixins | DR Pseudomonas aeruginosa/membrane/bacteriacide/narrow/High toxicity/ |
| Flucystocine | mycoses/nucleics/fungicide/narrow/High toxicity/ |
Created by:
jrjct1
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